HEMATOLOGY MCQ – Exercise 3

The multiple choice questions in this online test paper focuses on HEMATOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online HEMATOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. true regarding von Willebrand factor

large multimeric protein

present in plasma

present in extracellular matrix of subendothelial vessel

all of the above

Q 2. which antiplasmin inhibits plasmin

α1 antiplasmin

α2 antiplasmin

α3 antiplasmin

α4 antiplasmin

Q 3. most abundant receptor on the platelet surface is

Gp Ia/ IIa

Gp Ib/ IX

Gp IIb/ IIIa

Gp IV

Q 4. menorrhagia is a common symptom in women with

VWD

factor XI deficiency

symptomatic carriers of hemophilia A

all of the above

Q 5. formed element of blood that is not a component of the hemostatic system is

neutrophil

monocyte

red cell

platelet

Q 6. epistaxis is the most common symptom in

hemophilia A

Ehlres-Danlos syndrome

hereditary hemorrhagic telangiectasia

cushing’s syndrome

Q 7. following becomes an anticoagulant when activated by thrombin

antithrombin III

protein C

protein S

tissue factor pathway inhibitor

Q 8. following inhibits TF/FVIIa/FXa complex

activated protein C

protein S

tissue factor pathway inhibitor

all of the above

Q 9. tissue factor pathway inhibitor released by

heparin

streptokinase

urokinase

all of the above

Q 10. physiologic regulation of fibrinolysis is done by

plasminogen activator inhibitors (PAI-1 & PAI-2)

thrombin activatable fibrinolysis inhibitor

α2 antiplasmin

all of the above

Q 11. serine protease factor include

III

VIIa

Q 12. life threatening site of bleeding

bleeding into oropharynx

bleeding into central nervous system

bleeding into retroperitoneum

all of the above

Q 13. herb with potential antiplatelet activity

ginger

turmeric

garlic

all of the above

Q 14. following best relates to heparin

antithrombin III

protein C

protein S

all of the above

Q 15. platelet adhesion is mediated primarily by

von Willebrand factor

Gp IIb/IIIa

Gp Ia/IIa

fibronectin

Q 16. true regarding clopidogrel

thienopyridine

inhibits ADP mediated platelet aggregation

can precipitate or exacerbate bleeding symptoms

all of the above

Q 17. tissue factor is present on

subendothelial cellular components of vessel wall

circulating microparticles from monocytes

circulating microparticles from platelets

all of the above

Q 18. major components of the hemostatic system are

platelets , monocytes and red cells

plasma proteins

vessel wall

all of the above

Q 19. serine protease factor include

III

VIIa

Q 20. activated platelets releases

epinephrine

thrombin

adenosine diphosphate

all of the above

Q 21. following in endothelial cells has antithrombotic effect

prostacyclin

nitric oxide

EctoADPase/CD39

all of the above

Q 22. anticoagulant factor produced by endothelial cells is

heparin proteoglycans

antithrombin

thrombomodulin

all of the above

Q 23. endothelial cells activate fibrinolytic mechanisms through the production of

tissue plasminogen activator 1

urokinase

plasminogen activator inhibitor

all of the above

Q 24. plasminogen activators (tPA & uPA ) cleave which bond of plasminogen to generate the active enzyme plasmin

Arg460-Val461

Arg560-Val561

Arg660-Val661

Arg760-Val761

Q 25. platelet surface contains how many Gp IIb/ IIIa binding sites

~ 10,000

~ 25,000

~ 50,000

~ 10,0000

Q 26. following produced by endothelial cells acts as an anticoagulant

plasminogen activator inhibitor

thrombomodulin

prostacyclin

nitric oxide

Q 27. activating protein C acts as an anticoagulant by cleaving and inactivating activated factor

Q 28. platelet surface receptor Gp IIb/ IIIa binds to

thrombospondin

fibrinogen

collagen

all of the above

Q 29. true regarding thrombomodulin

transmembrane proteoglycan binding site for thrombin on endothelial cell surface

thrombin induced activation of protein C occurs physiologically on thrombomodulin

anticoagulant factor from endothelial cell

all of the above

Q 30. fibrin specific activity of plasmin is due to its

arginine binding sites

lysine binding sites

valine binding sites

leucine binding sites

HEMATOLOGY MCQ – Exercise 3

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