HEMATOLOGY MCQ – Exercise 6

The multiple choice questions in this online test paper focuses on HEMATOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online HEMATOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. massive splenomegaly is defined as spleen extending

>2cm below left costal margin

>4cm below left costal margin

>6 cm below left costal margin

>8 cm below left costal margin

Q 2. Abscopal effect refers to

ultrafiltration of abnormal RBCs

regression of systemic disease after splenectomy

increased tendency of enlarged spleen rupture

peritoneal seeding of splenic fragments

Q 3. causes of massive splenomegaly

CML

lymphomas

hairy cell leukemia

all of the above

Q 4. in elective splenectomy pneumococcal vaccine should be administered before surgery before how many weeks

1 week

2 weeks

3 weeks

4 weeks

Q 5. leukocytes include

NK cell

B lymphocyte

monocyte

all of the above

Q 6. in Castell method percussion in the lowest intercostals space is done

midclavicular line

anterior axillary line

midaxillary line

posteror axillary line

Q 7. excessive segmentation of nucleus of neutrophils is a manifestation of

folate or vitamin B12 deficiency

iron deficiency

thalassemia

repeated blood transfusion

Q 8. regarding leukocytes true statement includes

derived from common stem cell in bone marrow

three fourths of nucleated cells of bone marrow are committed to leukocyte production

their maturation in marrow is regulated by colony stimulating factors & interlekins

all of the above

Q 9. chronic manifestation of splenectomy include

Howel Jolly bodies

Heinz bodies

basophilic stippling

all of the above

Q 10. primary or azurophil granules contain

hydrolases

cathepsin G

myeloperoxidase

all of the above

Q 11. frequency of serious infection following splenectomy is highest within

first 6 months

first 1 year

first 3 years

first 5 years

Q 12. massive splenomegaly is defined as spleen that weighs

>250 gram

>500 gram

>750 gram

>1000 gram

Q 13. minimum number of stem cells necessary to support hematopoiesis is

100 to 200

200 to 300

300 to 400

400 to 500

Q 14. primary or azurophil granules are present in

myeloblast

promyelocyte

myelocyte

all of the above

Q 15. Nixon , Castell , or Barkun methods are used for splenic

inspection

palapation

percussion

auscultation

Q 16. true regarding spleen examination

auscultation may reveal venous hum or friction rub

bimanual palpation in right lateral decubitus position adds nothing to supine examination

reproducibility among examiners is better for palpation than percussion

all of the above

Q 17. seconday granules synthesized by myelocytes contain all except

acid hydrolases

lactoferrin

vitamin B12 binding protein

histaminase

Q 18. in a 80 kg person approximately neutrophils produced by hematopoietic system per day

~.3×1011

~1.3×1011

~2.3×1011

~3.3×1011

Q 19. specific or secondary granules are present in

myeloblast

promyeloyte

myelocyte

all of the above

Q 20. largest cell in size

myeloblast

promyelocyte

myelocyte

metamyelocyte

Q 21. percentage of neutrophil pool in bone marrow under normal conditions

~20%

~50%

~70%

~90%

Q 22. in Nixon method splenic enlargement is indicated when upper border of dullness above costal margin is

>4cm

>8cm

>12cm

>16cm

Q 23. regarding Pelger –Huet anamoly

benign disorder

majority of granules are bilobed

nucleus has spectacle like configuration

all of the above

Q 24. following azurophil granules has brod antimicrobial activity against bacteria , fungi & certain enveloped viruses

hydrolases

cathepsin G

myeloperoxidase

defensins

Q 25. maturation to neutrophil from metamyelocyte takes

2days

5days

7days

10days

Q 26. contraindication for splenectomy

iatrogenic splenic rupture

thrombocytopenia

presence of bone marrow failure

hairy cell leukemia

Q 27. following is true in postsplenectomy period

increased susceptibility to capsulated bacterial infection

no increased risk of viral infection

increased susceptibility to babesioisis

all of the above

Q 28. colony stimulating factors are produced by

monocytes

tissue macrophage

Stromal cells

all of the above

Q 29. packaging of secondary granule contents during myelopoiesis is controlled by

CCAAT / enhancer binding protein α

CCAAT / enhancer binding protein β

CCAAT / enhancer binding protein γ

CCAAT / enhancer binding protein €

Q 30. term splenosis best relates to

regression of systemic disease after splenectomy

ultrafiltration of abnormal RBCs

iatrogenic splenic rupture

ectopic spleen tissue

HEMATOLOGY MCQ – Exercise 6

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HEMATOLOGY MCQ – Exercise 6

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