Reproductive Biology / Medicine / Infertility MCQs – Exercise 15

The multiple choice questions in this online test paper focuses on Reproductive Biology / Reproductive Medicine / Infertility MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online Reproductive Biology / Reproductive Medicine / Infertility MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. Which of the following is TRUE regarding genetic testing in male infertility patients?

25% of all infertile males will have structural and numerical chromosomal abnormalities.

Genetic testing with karyotype and Y-chromosome microdeletion is indicated for all patients with azoospermia or severe oligospermia.

Y-chromosome microdeletion exists in 50% of patients with azoospermia.

CFTR mutations are identified in only 10% of patients with congenital bilateral absence of vas deferens (CBAVD).

Q 2. A female patient with complain that thought of sexual intercourse with her partner makes her uncomfortable and she tries to avoid such encounters. Most likely diagnosis

Sexual aversion disorder

Hypoactive sexual disorder

Vaginusmus

Dyspareunia

Q 3. A 65 year old male with history of hypertension and coronary artery disease presents with complain of erectile dysfunction. Most probable cause

Atherosclerosis

Hypertension

Hypothyroidism

none

Q 4. Following conditions can be diagnosed by preimplantation genetic diagnosis

Cystic fibrosis

Charcot Marie tooth syndrone

Duchenne muscular dystrophy

ALL

Q 5. True regarding the effect of cryptorchidism in male infertility

ryptorchid-induced testis failure include testicular dysgenesis, impaired endocrine axis, immunologic damage, and obstruction

These patients often have low FSH levels and small testes.

Both unilateral and bilateral cryptorchidism have equivalent effects on male fertility.

The level of the cryptorchid testis is not predictive of spermatogenic impairment.

Q 6. Types of ASA include all of the following EXCEPT:

sperm agglutinating types of antibodies that cause the agglutination of sperm and reduced motility.

sperm immobilizing types of antibodies that result in shaking of sperm.

spermatotoxic antibodies that result in a complement-dependent destruction of sperm.

acceptable normal values of ASA by World Health Organization (WHO) standards are less than 40%.

Q 7. Preimplantation genetic diagnosis probes disease-causing genes or chromosome aberrations in an ____ -celled preimplantation embryo.

Q 8. DNA fragmentation is associated with all of the following except

Smoking.

chemotherapy.

leukocytospermia.

vaginal lubricants

Q 9. Which hormones play a central role in regulation of Sertoli cell function?

LH, FSH

FSH, estradiol

Prolactin, LH

FSH, testosterone

Q 10. All of the following statements are true regarding radiologic examination of the male infertile patient EXCEPT:

Scrotal ultrasound is recommended for the diagnosis and potential treatment of subclinical varicoceles.

Testicular microlithiasis are noted in 3% of subfertile men but are not thought to be a precursor for testicular cancer

Testicular germ cell tumors are more common in men with infertility, and a screening ultrasound is recommended when there is any concern on physical examination.

Abdominal ultrasonography is indicated in men with unilateral absence of the vas deferens or CBAVD that is not associated with CFTR mutation due to an increased incidence of upper tract anomalies

Q 11. Which of the following is TRUE regarding ejaculatory duct obstruction (EJDO)?

Normal volume azoospermia is a common presentation for EJDO.

EJDO will often present with low-volume azoospermia.

Seminal vesicle width greater than 12 to 15 mm is suggestive of obstruction.

In a patient with suspected EJDO, seminal pH will usually be around 8.

Q 12. TRUE regarding reactive oxygen species (ROS) testing in semen?

ROS testing usually does not result in sperm damage or abnormal sperm parameters.

High levels of ROS are an independent marker of male factor infertility.

The chemiluminescence assay is not an accurate means to determine the presence of ROS.

ROS levels for healthy donors are 2.5 × 104 cpm/20 million.

Q 13. Late maturation arrest (MA) is characterized by:

the presence of only Sertoli cells and Leydig cells in the biopsy tissue.

elevated FSH and LH levels.

presence of elongated spermatids in the seminiferous tubules.

atients with normal sperm counts.

Q 14. Which of the following cells are used for preimplantation diagnosis

Polar body from oocytes

Blastomeres from cleavage stage embryos

Trophoectoderm cells from blastocysts

all

Q 15. The mechanism of varicocele-induced impaired spermatogenesis is thought to be:

heat injury from excess pooling of blood in dilated spermatic veins.

excess turbulent flow through dilated veins that causes a pressure injury to the testicle.

reflux of splenic metabolites, which is directly gonadotoxic.

higher testosterone levels in the peritesticular vasculature, which inhibit spermatogenesis.

Q 16. Most common type of sexual dysfunction in man

Erectile dysfunction

Premature ejaculation

Psychogenic disturbance

Retrograde ejaculation

Q 17. Indications for varicocelectomy include all of the following except

a subclinical varicocele in a patient with abnormal semen parameters

clinical varicocele in a male with known infertility.

adolescent males with ipsilateral testis size reduction of 20% compared with the contra lateral testis.

dull ipsilateral scrotal pain.

Q 18. The proportion of testicular volume comprised of seminiferous tubules in the human testis is:

5%.

10% to 20%.

50% to 60%.

70% to 80%.

Q 19. Embryologically, the vas deferens and body of the epididymis are derived from what developmental structure?

Müllerian ducts

Wolffian ducts

Urogenital ridge

Gubernaculum testis

Q 20. Following conditions can be diagnosed by preimplantation genetic diagnosis

CAH

Fragile X syndrome

Beta thallessemia

all

Q 21. The majority of the fluid in the male ejaculate is derived from:

the epididymides.

the ejaculatory ducts.

the seminal vesicles.

the prostate.

Q 22. A patient present with history of ansomia azoospermia, bilateral small testes and Gynaecomastia. Best treatment is

Testosterone replacement

Clomiphene

Bromocriptine

Gonadotropins

Q 23. Regarding semen abnormalities in infertility all statements are true except

Endocrinopathies are rarely observed in oligospermic males with sperm counts greater than 10 mil/mL.

Only 25% of males presenting for an infertility evaluation will have normal bulk semen parameters.

Teratospermia is a common finding and of minimal clinical significance in the absence of bizarre morphology.

Asthenospermia is often iatrogenic from delayed processing in the andrology laboratory.

Q 24. True regarding outcomes for varicocele ligation

An average increase in motility by 20%

Improved semen parameters in about two thirds of patients

Improvement in semen parameters in men with genetic infertility (e.g., Y-chromosome microdeletion)

Spontaneous fertilization rates of 75%

Q 25. All of the following warrant an endocrine evaluation in a male infertility patient except

oligospermia with counts less than 10 mil/mL.

erectile dysfunction.

decreased libido.

premature ejaculation

Q 26. A patient with history of tall stature during childhood and stop growing halfway and on examination found to have large phallus indicative of mild form of CAH. Correct statement regarding his fertility potential

may recover spermatogenesis if he starts treatment with gonadotropins.

He is likely to cause a pregnancy with or without treatment with corticosteroids

He needs an MRI of the head to accurately diagnose the pituitary lesion

Exogenous testosterone should be given to the patient to support spermatogenesis.

Q 27. Initial hormone evaluation in an infertile man with severe oligospermia includes:

testosterone and FSH.

FSH and LH.

FSH, LH, and prolactin.

FSH and inhibin B.

Q 28. A 35 year female patient complain of tightening of vagina without pain during intercourse since her early twenties,most probable diagnosis

Hypothyroidism

Sexual trauma

Endometriosis

PCOS

Q 29. A 35 year old patient presents with new onset erectile dysfu nction also complaining of Difficulty with his vision since last 4 months. Best treatment for this patient is

Cabergoline

Testosterone

Gonadotropins

Bromocriptine

Q 30. All of the following statements are true regarding azoospermia EXCEPT:

Pretesticular etiologies of azoospermia are usually endocrine in nature.

Testicular cause of azoospermia is also known as primary testis failure.

Secondary testis failure is characterized by high serum gonadotrophin levels and small testis size.

Low-volume azoospermia with normal testis size and palpable vas is a common presentation for testicular failure.

Reproductive Biology / Medicine / Infertility MCQs – Exercise 15

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Reproductive Biology / Medicine / Infertility MCQs – Exercise 15

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