HEMATOLOGY MCQ – Exercise 17

The multiple choice questions in this online test paper focuses on HEMATOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online HEMATOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. spur cell anemia is due to

clostridium welchii infection

HELLP syndrome

severe hepatocellular disease

hemolytic uremic syndrome

Q 2. action of CD 59

inhibits insertion of C9 into cell membrane

binds C3b

inhibiting C3 convertases

all of the above

Q 3. hypoproliferative anemia include all except

aplastic anemia

myelodysplasia (MDS)

pure red cell aplasia (PRCA)

congenital dyserythropoietic anemia

Q 4. cold agglutinin disease is related to

familial cold autoinflammatory syndrome

cold urticaria

waldenstorm macroglobulinemia

systemic mastocytosis

Q 5. aplastic anemia is strongly associated with

transfusion associated graft versus host disease

eosinophilic fascitis

SLE

all of the above

Q 6. pathways of activation of complement includes

classical pathway

mannose binding lectin pathway

alternative pathway

all of the above

Q 7. in PNH defective gene is

HNF4α

PIG-A

BRCA1

CFTR

Q 8. true regarding association between following drugs and aplastic anemia

benzene

chloramphenicol

carbamazepine

all of the above

Q 9. aplastic anemia is strongly associated with

PAN

schnitzlers syndrome

wegner’s granulomatosis

eosinophilic fascitis

Q 10. surface membrane of a spur cell (acanthocytes) contain excess of

phospholipid

cholesterol

triglycerides

glycoprotein

Q 11. most cases of aplastic anemia are

idiopathic

due to drug exposure

due to immune diseases

due to inherited disorders

Q 12. test useful in diagnosing PNH

acidified serum lysis test (Ham’s test)

sucrose lysis test

analysis of GP1 linked proteins

all of the above

Q 13. in hemolysis level of unconjugated bilirubin never exceeds

1 to 2 mg/dL

2 to 3 mg/dL

3 to 4 mg/dL

4 to 5 mg/dL

Q 14. following can directly parasitize RBCs and cause severe hemolysis

bartenelllosis

malarria

babesiosis

all of the above

Q 15. most important protective RBC membrane protein

CD 29

CD 39

CD 49

CD 59

Q 16. Burr cells seen in

severe hepatocellular disease

uremia

DIC

HELLP syndrome

Q 17. not a late effect of irradiation

aplastic anemia

MDS

leukemia

all of the above

Q 18. false regarding PNH

intracorpuscular defect acquired at stem cell level

hemolytic anemia

arterial thrombosis

bone marrow failure

Q 19. false regarding PNH

hemolysis due to activation of complement

hemosiderinuria is usually absent

granulocytopenia and thrombocytopenia

may present as Budd Chiari syndrome

Q 20. fraction of lactate dehydrogenase (LDH) is elevated by accelerated RBC destruction

Q 21. drugs causing warm antibody immunohemolytic anemia

α methyl dopa

penicillin

quinidine

all of the above

Q 22. following is diagnostic of PNH

CD59-, CD 55-

CD59+, CD 55-

CD59-, CD 55+

CD59+, CD 55+

Q 23. urine is positive with benzidine reaction in

hemoglobinuria

hematuria

myoglobinuria

all of the above

Q 24. transient aplastic crisis in hemolytic anemia is due to

hepatitis

infectious mononucleosis

parvovirus B19

all of the above

Q 25. RBC membrane is unstable at temperature above

38◦C

42◦C

46◦C

49◦C

Q 26. pathways of activation of complement system coverage at the point of cleavage of

Q 27. Eculizumab binds specifically to

Q 28. true about Haptoglobin

seum concentration is ~ 1.0 g/L

low or absent is significant hemolysisia

hemoglobin-haptoglobin complex is cleared rapidly by mononuclear phagocyte

all of the above

Q 29. false about haptoglobin

α globulin

binds to heme in hemoglobin

decreased in hepatocellular disease

increased in inflammatory states

Q 30. stains used to detect hemosiderin in urinary sediment

Prussian blue

Giemsa’s stain

methylene blue

crystal violet

HEMATOLOGY MCQ – Exercise 17

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HEMATOLOGY MCQ – Exercise 17

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