HEMATOLOGY MCQ – Exercise 24

The multiple choice questions in this online test paper focuses on HEMATOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online HEMATOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. myeloma causes enlargement of which of the folowing

spleen

lymph nodes

GALT

none of the above

Q 2. immune deficiency in myeloma patients is due to

diffuse hypogammaglobulinemia

low granulocyte lysozyme content

abnormalities in complement functions

all of the above

Q 3. drugs useful in the treatment of myeloma

vincristine

doxorubicin

melphalan

all of the above

Q 4. hyperviscosity in multiple myeloma may cause

headache

visual disturbances

retinopathy

all of the above

Q 5. following are associated with poor prognosis in a patient of multiple myeloma

elevated levels of LI-6

high labeling index

high levels of lactate dehydrogenase

all of the above

Q 6. sensory neuropathy occurs in

multiple myeloma

MGUS

thalidomide and Bortezomib therapy

all of the above

Q 7. hyperviscosity in multiple myeloma caused by following paraproteins

IgM

IgG3

IgA

all of the above

Q 8. extramedullary plasmocytoma usually involves

lung associated lymphatic tissue

gut associated lymphatic tissue

submucosal lymphoid tissue of nasopharynx or sinuses

any of the above

Q 9. bone marrow plasma cells

CD130+

CD134+

CD138+

CD142+

Q 10. which of the IgG subclass causes hyperviscosity most commonly

IgG1

IgG2

IgG3

IgG4

Q 11. parameters besides serum β2-microglobulin is used in international staging system for myeloma

serum albumin

hemoglobin

serum calcium

serum creatinine

Q 12. in myeloma following is the single most powerful predictor of survival and can substitute for staging

serum beta 2 microglobulin

lactate dehydrogenase

thymidine kinase

% plasma cells in marrow

Q 13. earliest manifestation of tubular damage in multiple myeloma is

medullary cystic kidney disease

adult Fanconi syndrome

nephronophthisis

all of the above

Q 14. drug that must not be used in myeloma patients who are transplant candidates

melphalan

thalidomide

high dose pulsed glucocorticoids

bortezomib

Q 15. true regarding myeloma

all myeloma is preceded by MGUS

serum alkaline phosphatase is normal

dipsticks for detecting proteinuria not reliable for light chains

all of the above

Q 16. triad of multiple myeloma includes all except

marrow plasmocytosis

bence jones proteins in urine

lytic bone lesions

serum and /or urine M component

Q 17. normal serum viscosity is

1.2

1.4

1.6

1.8

Q 18. regarding MGUS all are true except

<10% bone marrow plasma cells

<3g/dL of M components

urinary bence jones sproteins

no bone lesions

Q 19. anion gap in myeloma patients

increased

decreased

normal

any of the above

Q 20. true statement regarding anemia in multiple myeloma

normocytic , normochromic

granulocytopenia very rare

thrombocytopenia very rare

all of the above

Q 21. most common cause of renal failure in multiple myeloma patients

recurrent infections

hypercalcemia

hyperuricemia

infiltration of kidney by myeloma cells

Q 22. for diagnosis of myeloma, marrow plamacytosis must be

>5%

>10%

>15%

>20%

Q 23. following factor is associated with higher incidence of progression of MGUS to myeloma

non-IgG subtype

abnormal kappa / lambda free light chain ratio

serum M protein >1.5 g/dL

all of the above

Q 24. following regarding renal failure in myeloma patients is true

protein in urine is nearly all light chains

proteinuria is not accompanied by hypertension

susceptible to acute renal failure if dehydrated

all of the above

Q 25. symptoms of hyperviscosity occurs at level of

1 to 2

3 to 4

4 to 5

5 to 6

Q 26. hyperviscosity in multiple myeloma most commonly caused by which paraprotein

IgA

IgG

IgD

IgM

Q 27. percentage of patients with development of MGUS develops myeloma

~1%

~2%

~3%

~4%

Q 28. following are included in diagnosis of multiple myeloma

hemoglobin

serum calcium and degree of skeletal involvement

M component

all of the above

Q 29. in MGUS most common immunoglobulin effected

IgG

IgM

IgA

biclonal gammopathies

Q 30. myeloma staging system includes

ann arbor staging system

binet staging system

RAI staging system

durie salmon staging system

HEMATOLOGY MCQ – Exercise 24

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HEMATOLOGY MCQ – Exercise 24

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