ENDOCRINOLOGY MCQs – Exercise 16

The multiple choice questions in this online test paper focuses on ENDOCRINOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online ENDOCRINOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. statement suggestive of Cushing’s syndrome

urine free cortisol >50µg/day

plasma cortisol >5µg/dL after standard low dose dexamethasone suppression test

absence of normal fall of plasma cortisol at midnight

all of the above

Q 2. principal drug for the treatment of adrenocortical carcinoma

mitotane

ketoconazole

mifepristone

metyrapone

Q 3. criteria for the diagnosis of primary aldosteronism include

diastolic hypertension without edema

hyposecretion of renin (low PRA) that do not increase during volume depletion

hypersecretion of aldosterone that does not suppress in response to volume expansion

all of the above

Q 4. features suggestive of adrenocortical carcinoma include all except

size > 4-6 cm

soft tissue calcification visible on CT

tumor inhomogeneity

low enhanced CT values (<10HU)

Q 5. which feature of Cushing’s syndrome is considered more specific

hypertension

osteoporosis

broad violaceous cutaneous striae

obesity

Q 6. McCune –Albright syndrome caused by activating mutations in

GNAS-1

PKA

CREB

StAR

Q 7. which of the following chronic granulomatous disease affect adrenal gland

tuberculosis

histoplamosis

coccidiodomycosis

all of the above

Q 8. as compared to essential hypertension , patients with primary aldosteronism have a higher incidence of

LVH

albuminuria

stroke

all of the above

Q 9. commonest feature of Cushing’s syndrome

centripetal obesity

hypertension

hirsutism

proximal myopathy

Q 10. primary pigmented nodular adrenal disease (PPNAD) best related to

Crow Fukase syndrome

Hirschprung disease

Carney’s complex

von Hippel –Lindau syndrome

Q 11. secondary aldosteronism occurs in association with

accelerated phase of hypertension

underlying disoreder

Bartter and Gitelman syndrome

all of the above

Q 12. in Cushing’s syndrome, after a standard low dose dexamethasone suppression test, failure of urinary cortisol to fall to

<10 µg/day

<20 µg/day

<30 µg/day

<40 µg/day

Q 13. decreased bone mineralization due to use of steroids is particularly pronounced in

children

adults

elderly

all of the above

Q 14. normal plasma ACTH level is

<60 pg/ml

<80 pg/ml

<100 pg/ml

<120 pg/ml

Q 15. typical of Cushing’s syndrome includes

moon facies

buffalo hump

truncal obesity

all of the above

Q 16. what ratio of serum aldosterone to plasma renin activity suggests autonomy of aldosterone secretion

>10

>15

>20

>30

Q 17. regarding Ectopic ACTH syndrome all are true except

caused by non pituitary tumors secreting ACTH/CRH

bilateral adrenal hyperplasia

typical signs and symptoms of Cushing’s syndrome present

hypokalemic alkalosis is a prominent manifestation

Q 18. drug that is use in primary aldosteronism is

spironolactone

eplerenone

triamterene

all of the above

Q 19. Carney’s complex features include

cardiac myxomas

hyperlentiginosis

sertoli cell tumors

all of the above

Q 20. increased production of aldosterone occurs in secondary aldosteronism in response to

activation of sympathetic system

activation of parasympathetic system

activation of renin angiotensin system

all of the above

Q 21. Ectopic ACTH syndrome causes includes

oat cell bronchogenic carcinoma

carcinoid tumors of thymus, pancreas, ovary

medullary carcinoma of thyroid

all of the above

Q 22. regarding bilateral cortical nodular hyperplasia true statement includes

~80% of patients with primary aldosteronism

hypokalemia less likely

less radiologic evidence for adrenal pathology

all of the above

Q 23. in ACTH independent macronodular hyperplasia (AIMAH) which receptor is ectopically expressed in the adrenal gland

vasopressin

serotonin

all of the above

Q 24. cause of ACTH independent Cushing’s syndrome includes

ACTH independent macronodular hyperplasia (AIMAH)

primary pigmented nodular adrenal disease (PPNAD)

McCune –Albright syndrome

all of the above

Q 25. chemical adrenelectomy can be done by

ketoconazole

mitotane

metyrapone

all of the above

Q 26. adrenal insufficiency appears when adrenal glands are destroyed more than

>25%

>50%

>75%

>90%

Q 27. a 24 hour urine free cortisol of what level is suggestive of Cushing’s syndrome

>5 µg/day

>25 µg/day

>50 µg/day

>150 µg/day

Q 28. most common cause of Cushing’s syndrome

iatrogenic administration of steroids

adrenal macronodular hyperplasia

adrenal micronodular hyperplasia

adrenal neoplasia

Q 29. secondary aldosteronism is a feature of

cirrhosis

nephritic syndrome

CCF

all of the above

Q 30. specific adrenal antigens to which autoantibodies may be directed include

SOX9

21-hydroxylase

RSPO1

CYP19

ENDOCRINOLOGY MCQs – Exercise 16

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