ENDOCRINOLOGY MCQs – Exercise 17

The multiple choice questions in this online test paper focuses on ENDOCRINOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online ENDOCRINOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. mutant gene in type 1 polyglandular syndrome is on

chromosome 12

chromosome 16

chromosome 18

chromosome 21

Q 2. which drug may cause or potentiate adrenal insufficiency

rifampin

phenytoin

ketoconozole

all of the above

Q 3. early sign of hyperpigmentation in Addison’s disease

darkening of areolae of nipples

bluish black patches on mucous membrane

persistent tanning following sun exposure

dark freckles

Q 4. 21 hydroxylase gene is located on chromosome

Q 5. isolated aldosterone deficiency occurs in

protracted heparin administration

pretectal disease of nervous system

severe postural hypotension

all of the above

Q 6. primary and secondary adrenal insufficiency can be distinguished by measuring

renin

aldosterone

angiotensin I

angiotensin II

Q 7. Hypertensive variant of CAH is due to deficiency of

17 hydroxylase

21 hydroxylase

11β hydroxylase

3β-HSD2

Q 8. true regarding secondary adrenal insufficiency

no hyperpigmentation

low ACTH level

near normal aldosterone levels

all of the above

Q 9. acute adrenocortical insufficiency results from

meningococcal septicemia, pseudomonas septicemia

anticoagulant disorder , coagulation disorder

pregnancy , rapid withdrawal of steroids

all of the above

Q 10. CAH caused by deficiency of 21 hydroxylase is characterized by

cortisol deficiency

with or without aldosterone deficiency

androgen excess

all of the above

Q 11. following cosyntropin , increment of less than what between peak and baseline cortisol levels defines adrenal insufficiency

<3 µg/dL

<6 µg/dL

<9 µg/dL

<12 µg/dL

Q 12. during fever in adrenal insufficiency dose of hydrocortisone should be

keep the same

doubled

tripled

quadrupled

Q 13. what random cortisol value excludes the diagnosis of relative adrenal insufficiency

>24 µg/dL

>34 µg/dL

>44 µg/dL

>54 µg/dL

Q 14. In acutely ill patients regarding cortisol true statement includes

cortisol levels rise to four to six fold

diurnal variation is abolished

unbound fraction of cortisol rises

all of the above

Q 15. C in APECED gene stands for

carcinoma

candidiasis

calcinosis

caif-au -lait

Q 16. in Addison’s disease there is increased incidence of

chronic lymphocytic thyroiditis, hypo or hyperthyroidism

premature ovarian failure, pernicious anemia

type 1 diabetes mellitus, myasthenia gravis

all of the above

Q 17. type I polyglandular syndrome consists of all except

parathyroid insufficiency

adrenal insufficiency

chronic mucocutaneous candidiasis

myasthenia gravis

Q 18. functional or relative adrenal insufficiency is

adrenal insufficiency on withdrawal of long term steroids

subnormal cortisol production during acute severe illness

failure to take replacement therapy in adrenal insufficiency

ineffective replacement therapy in adrenal insufficiency

Q 19. most common form of CAH is due to impairment of

17 hydroxylase

21 hydroxylase

11β hydroxylase

3β-HSD2

Q 20. in type II polyglandular syndrome mutant gene is located on

chromosome 4

chromosome 6

chromosome 8

chromosome 10

Q 21. very high concentration of which is diagnostic of 21 hydroxylase deficiency

androstenedione

11-deoxycortisol

17-hydroxyprogesterone

pregnenolone

Q 22. hematologic abnormalities seen in adrenal insufficiency is

normocytic anemia

relative lymphocytosis

moderate eosinophilia

all of the above

Q 23. most frequent presentation in adrenal insufficiency

weakness

pigmentation of mucous membrane

salt craving

diarrhea

Q 24. during stress plasma cortisol levels should be constantly maintained at

10 µg/dL

20 µg/dL

30 µg/dL

40 µg/dL

Q 25. following present in primary adrenocortical insufficiency

dehydration

hyponatremia

hyperkalemia

all of the above

Q 26. in rapid ACTH stimulation test, cortisol level at 60 minutes after cosyntropin should be

>6 µg/dL

>12 µg/dL

>18 µg/dL

>24 µg/dL

Q 27. at what dose of hydrocortisone in Addison’s disease mineralocorticoid administration is unnecessary

>10 mg/day

>40 mg/day

>80 mg/day

>100 mg/day

Q 28. to simulate normal diurnal adrenal rhythm what proportion of total glucocorticoids should be given in the morning

one third

one half

two third

three fourth

Q 29. what value of corticotrophin stimulated concentration of 17 hydroxyprogesterone is diagnostic of 21-hydroxylase deficiency

>15 nmol/L

>25 nmol/L

>35 nmol/L

>45 nmol/L

Q 30. in rapid ACTH stimulation test dose of cosyntropin is

50 µg

150 µg

250 µg

500 µg

ENDOCRINOLOGY MCQs – Exercise 17

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