ENDOCRINOLOGY MCQs – Exercise 22

The multiple choice questions in this online test paper focuses on ENDOCRINOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online ENDOCRINOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. increased ketone body formation in DKA is mediated by enzyme

HMG CoA reductase

CPT-I

CPT-II

acyl CoA transferase

Q 2. drugs which may cause false positive reaction in the nitroprusside test to detect urine ketones include

captopril , penicillamine

atorvastatin , azithromycin

aspirin , cephalosporins

all of the above

Q 3. HNF (hepatocyte nuclear transcription factor) is expressed in

liver

pancreatic islets

kidney

all of the above

Q 4. in DKA with insulin therapy hyperglycemia improves due to

insulin mediated glucose disposal

reduced hepatic glucose release

rehydration

all of the above

Q 5. cerebral edema in DKA is seen most frequently in

children

adults

elderly

all of the above

Q 6. serum sodium is reduced by how much level for every 100mg/dL rise in serum glucose

1meq/L

1.2 meq/L

1.4 meq/L

1.6 meq/L

Q 7. islet cell dysfunction caused by all except

chronic hyperglycemia

hyperlipidemia

hypoglycemia

islet cell autoantibodies

Q 8. serum osmolality formula

{2× (serum Na + K) + plasma glucose(mg/dL)/18 +BUN/2.8}

{3× (serum Na + K) + plasma glucose(mg/dL)/18 +BUN/2.8}

{4× (serum Na + K) + plasma glucose(mg/dL)/18 +BUN/2.8}

{5× (serum Na + K) + plasma glucose(mg/dL)/18 +BUN/2.8}

Q 9. glucose toxicity refers to

acute hyperglycemia impairing islet function

chronic hyperglycemia impairing islet function

seizures in hyperglycemia

none of the above

Q 10. MODY 3 is caused by mutations in

HNF-4 alpha

HNF-1 alpha

HNF-1 beta

all of the above

Q 11. elevated amylase in DKA of which origin

salivary

gastric

pancreatic

all of the above

Q 12. all are proved to delay DM except

life style modification, metformin

metformin, acarbose

ramipril , pravastatin

atorvastatin , NSAIDs

Q 13. pancreatic beta cells secretes

ptyalin

amylin

amylase

lipase

Q 14. features of PCOS include

chronic anovulation

hyperandrogenism

insulin resistance

all of the above

Q 15. in type 2 DM increased postprandial plasma glucose is predominantly due to

increased hepatic glucose output

decreased peripheral utilization of glucose

both f the above

none of the above

Q 16. in DKA which salt of potassium is avoided for replacement

chloride

phosphate

acetate

all of the above

Q 17. precipitating event in DKA includes

infection

infarction

cocaine

all of the above

Q 18. in type 2 DM increased fasting plasma glucose is predominantly due to

increased hepatic glucose output

decreased peripheral utilization of glucose

both f the above

none of the above

Q 19. risk factors for type 2 DM include all except

hypertension

acanthosis nigricans

PCOD

ataxia telangiectasia

Q 20. interference from which of the following may falsely elevates the serum creatinine measurement in DKA

acetoacetate

hypertriglyceridemia

hyperglycemia

blood urea

Q 21. predominant role in insulin resistance played by

pre receptor defects

receptor defects

post receptor defects

all of the above

Q 22. in DKA, following insulin therapy, decline in glucose within first 1 to 2 hours is mostly related to

insulin mediated glucose disposal

reduced hepatic glucose

rehydration

all of the above

Q 23. following intravenous solution is preferred for initial use in DKA to reduce hyperchloremia

.45% saline

normal saline

lactated ringer solution

any of the above

Q 24. regarding MODY true statement includes all except

monogenic

autosomal dominant

MODY 4 is due to mutation in IPF-1

MODY 1 is due to mutation in glucokinase gene

Q 25. insulin should not be administered in DKA until potassium level is greater than

3 meq/L

3.1 meq/L

3.2 meq/L

3.3 meq/L

Q 26. adipocytes secretes

leptin, adiponectin

resistin , retinol binding protein 4

TNF alpha , non esterified free fatty acids

all of the above

Q 27. elevated free fatty acids level can leads to

impair glucose utilization in skeletal muscle

promote glucose production by liver

impair beta cell function

all of the above

Q 28. decreased ratio of insulin to glucagon in liver promotes

gluconeogenesis

glycogenolysis

ketone body formation

all of the above

Q 29. in DKA, following insulin therapy following resolves first

acidosis

ketosis

hyperglycemia

any of the above

Q 30. nitroprusside reaction detects

acetoacetate

acetone

beta hydroxy butyrate

a and b

ENDOCRINOLOGY MCQs – Exercise 22

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ENDOCRINOLOGY MCQs – Exercise 22

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