ENDOCRINOLOGY MCQs – Exercise 28

The multiple choice questions in this online test paper focuses on ENDOCRINOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online ENDOCRINOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. Prader-Willi syndrome is characterized by all except

obesity, hypogonadism

tall stature, lean and thin constitution

hypotonic musculature, short stature

mental retardation, small hands and feets

Q 2. gonadotropin independent precocious puberty can be treated with all except

long acting GnRH analogues

ketoconazole

spironlactone

testolactone

Q 3. in healthy young men testosterone range is

50 to 180 ng/dL

180 to 225 ng/dL

225 to 500 ng/dL

300 to 1000 ng/dL

Q 4. true statements include

elevated LH indicates with low testosterone level indicates primary defect at testicular level

increased FSH indicates damage to seminiferous tubules

decreased inhibin B levels are associated with damage to seminiferous tubules

all of the above

Q 5. gonadotropin independent causes of precocious puberty in boys include all except

hCG secreting tumors

hyperthyroidism

congenital adrenal hyperplasia

hypothyroidism

Q 6. testicular size greater than what length generally indicates that the child has entered puberty

>1.5 cm

>2.0 cm

>2.5 cm

>3.5 cm

Q 7. McCune-Albright syndrome caused by somatic mutations in

Gs alpha subunit

Gs beta subunit

Gs gamma subunit

Gs delta subunit

Q 8. Prader orchidometer is used to measure

testicular volume

testicular length

testicular area

testicular density

Q 9. true regarding congenital adrenal hyperplasia includes

chronic ACTH stimulation

low LH

small testes

all of the above

Q 10. which of the following categories of delayed puberty is more common in girls than boys

constitutional delay of growth and puberty

functional hypogonadotropic hypogonadism caused by systemic illness or malnutrition

hypogonadotropic hypogonadism caused by genetic or acquired defects in the hypothalamic-pituitary region

hypergonadotropic hypogonadism secondary to primary Gonadal failure

Q 11. familial male limited precocious puberty can be treated by

inhibitors of testosterone synthesis-ketoconazole

androgen receptor antagonists-flutamide

aromatase inhibitors-anastrazole

all of the above

Q 12. androgen dependent event includes

early morning erections

frequency and intensity of sexual thoughts

frequency of masturbation or intercourse

all of the above

Q 13. testotoxicosis is an autosomal dominant disorder due to activating mutations in LH receptor related to

McCune-Albright syndrome

familial male limited precocious puberty

congenital adrenal hyperplasia

none of the above

Q 14. in prepubertal boys with Cryptorchidism following is measured to detect the presence of testes

inhibin B

MIS

testosterone

all of the above

Q 15. regarding GnRH stimulation testing all are true except

iv administration of 300 µg of GnRH

measures LH and FSH at baseline

measures LH and FSH at 30 and 60 minutes after iv administration of GnRH

minimally acceptable response is a two fold increase in LH and 50% increase in FSH

Q 16. what percentage of circulating testosterone is free

.05 to .3%

.3 to .8%

.5 to 3%

1.5 to 5.5%

Q 17. normal semen ejaculate volume is

1 to 3 ml

2 to 6 ml

5 to8 ml

8 to 10 ml

Q 18. characteristic skin lesion in McCune-Albright syndrome includes

café au lait spots

telangiectasia

erythroderma

scarring alopecia

Q 19. before what age in boys puberty is considered as precocious

9 years

10 years

11 years

12 years

Q 20. Kallman syndrome is transmitted as X linked and due to mutation in

KAL1 gene encoding kalmin

KAl2 gene encoding anosmin

GPR54 gene encoding migrin

DAX1 gene encoding neurokinin

Q 21. breast enlargement in prepubertal boys can result from

familial aromatase excess

estrogen producing tumors in adrenal gland

sertoli cell tumors in testis

all of the above

Q 22. regarding hCG stimulation test all are true except

administer 150 to 400 IU hCG intramuscularly

measure testosterone levels at 0,24,48,72 and 120 hours

in adult male acceptable response is a doubling of testosterone concentration

in prepubertal boys increase in testosterone to > 150 ng/dL indicates the presence of testicular tissue

Q 23. length and volume of normal testes respectively are

.5 to 2.5 cm and 5-10 mL

1.5 to 3.5 cm and 10-15 mL

3.5 to 5.5 cm and 15-25 mL

5.5 to 7.5 cm and 25-35 mL

Q 24. familial hypogonadotropic hypogonadism is transmitted most commonly as

X linked

autosomal recessive

autosomal dominant

autosomal codominant

Q 25. true regarding central precocious puberty

premature activation of GnRH pulse generator

gonadotropins levels inappropriately elevated for age

less common in boys than girls

all of the above

Q 26. which of the following is true for eununchoid proportions

arm span is less than height

arm span is equal to height

arm span is greater than height

none of the above

Q 27. in boys puberty is considered delayed if it has not ensued by the age

12 years

13 years

14 years

15 years

Q 28. Laurence Moon syndrome is an autosomal recessive disorder characterized by all except

obesity, polydactyly

hypogonadism, retinitis pigmentosa

short stature, small hands and feet

mental retardation, polydactyly

Q 29. most common cause of delayed puberty is constitutional delay and should be suspected when there is

positive family history

delayed bone age

short stature

all of the above

Q 30. bioavailable testosterone refers to

total testosterone

unbound testosterone + testosterone bound to albumin

unbound testosterone

testosterone bound to albumin

ENDOCRINOLOGY MCQs – Exercise 28

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