GASTROINTESTINAL AND LIVER DISEASE – Exercise 19

The multiple choice questions in this online test paper focuses on GASTROINTESTINAL AND LIVER DISEASE MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online GASTROINTESTINAL AND LIVER DISEASE MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. Whipples disease is caused by

Tropheryma whippeli

treponema whippeli

toxoplsma whippeli

tenoderma whippeli

Q 2. IBD associated with all except

turner’s syndrome

Down syndrome

selective IgA deficiency

hereditary angioedema

Q 3. Creeping fat in CD term denotes

excessive enlargement of omentum

necrosis of omentum

projections of thickened mesentery encasing bowel

fatty adhesions

Q 4. false about protein losing enteropathy

excess protein loss into GIT

low serum albumin & globulin in absence of renal & hepatic disease

α 1 antitrypsin clearance can be useful in diagnosis

lymphocytosis supports diagnosis

Q 5. following cells induce transmural granulomatous inflammation that resembles CD

TH1 cells

TH2 cells

TH17 cells

all of the above

Q 6. if two parents have IBD chance of each child being affected

36%

45%

66%

72%

Q 7. which of the following is aka lymphotoxin

TNFα

TNFβ

IFNα

IFNγ

Q 8. regarding fecal calprotectin true statement include

levels correlates well with histologic inflammation

predicts relapses

detects pouchitis

all of the above

Q 9. false statement regarding UC & crohns disease

peak age of onset of UC & CD is 15—30 years

second peak occurs between 60—80 years

appendicectomy aggravates UC

IBD run in families

Q 10. false about whipples disease

multisystem disease

T.whipplei outside macrophages indicates active disease

T.whipplei can not be grown on culture

drug of first choice TMP/SMX for 1 year

Q 11. nonmalignant mortality in IBD cases is maximum during

first year of disease

after 5 years of disease

after 10 years of disease

after 15 years of disease

Q 12. predisposing factor for UC include all except

jewish ethinicity

high socioeconomic status

smoking

Hermansky –Pudalk syndrome

Q 13. percentage of UC patients having involvement of whole colon

10%

20%

30%

40%

Q 14. highly sensitive & specific marker for detecting intestinal inflammation

fecal lactoferrin

fecal transferrin

fecal hemolysin

fecal reactin

Q 15. false about complications of UC

toxic megacolon means a transeverse colon with diameter >6cm with loss of haustration

toxic megacolon can be triggered by electrolyte abnormalities and narcotics

in toxic colitis and severe ulcerations, bowel may perforate without first dilating

UC patients never develop anal fissures, perianal abscesses

Q 16. false statement about T.whipplei is

gram positive

actinobacterium

low virulence, low infectivity

PAS + macrophages in small intestine

Q 17. in the presence of frequent reccurences of bacterial overgrowth syndrome treatment strategy most effective

antibiotics for 1 week per month

antibiotics for ~3 weeks

antibiotics until symptoms remit

antibiotics continously

Q 18. following can cause protein losing enteropathy

peripheral vascular disease

chronic pericarditis

hemolytic uremic syndrome

hypothyroidism

Q 19. IFNγ is secreted by

TH1 cells

TH2 cells

TH17 cells

all of the above

Q 20. in backwash ileitis part of colon involved is

ascending colon

descending colon

transverse colon

whole colon

Q 21. lack of immune responsiveness of gut mucosal immune system to dietary antigens is best related to

intestinal tolerance

gastric tolerance

oral intolerance

all of the above

Q 22. hypoproteinemia in intestinal lymphangiectasia should be treated with

SCFA

MCT

LCFA

all of the above

Q 23. regarding fecal calprotectin true statement include

calcium binding

has antimicrobial properties

predict relapses in IBD

all of the above

Q 24. most common neurologic manifestation of classic Whipple’s disease

cognitive change

supranuclear ophthalmoplegia

oculomasticatory or oculofascialskeletal myorhythmia

ataxia

Q 25. features of UC include all except

barium enema shows fine mucosal granularity

color button ulcers seen in barium enema

loss of haustration occurs in early disease

colon can become short & narrowed

Q 26. in severe ulcerative colitis number of bowel movements per day is

2—3

3—4

4—5

Q 27. regarding pathology of UC which is false

mucosal disease involving rectum and colon

proximal spread occurs in continuity

sandpaper like appearance of mucosa reflects severe inflammation

inflammatory polyps (pseudopolyps) are due to epithelial regeneration

Q 28. cobblestone mucosa in CD is mainly seen in

sigmoid colon

transeverse colon

ileum

rectum

Q 29. regarding fecal calprotectin true statement include

neutrophilic cytosolic protein

resistant to colonic bacterial degradation

formerly called L1 protein

all of the above

Q 30. following cells induce superficial mucosal inflammation resembling UC

TH1 cells

TH2 cells

TH17 cells

all of the above

GASTROINTESTINAL AND LIVER DISEASE – Exercise 19

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GASTROINTESTINAL AND LIVER DISEASE – Exercise 19

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