GASTROINTESTINAL AND LIVER DISEASE – Exercise 29

The multiple choice questions in this online test paper focuses on GASTROINTESTINAL AND LIVER DISEASE MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online GASTROINTESTINAL AND LIVER DISEASE MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. HBeAg negative chronic hepatitis B or e-CHB is characterized by all except

HBsAg positive for at least 6 months

HbeAg positive

anti-HBe positive

HBV DNA detectable in serum unamplified assays

Q 2. HBV escapes mutants best relate to which of the following

single base substitution

single base addition

single amino acid substitution

single amino acid addition

Q 3. following about chronic HBV infection is false

HBsAg detectable > 6 months

IgG anti-HBc present

anti-HBs low to absent

none of the above

Q 4. HBeAg differs from HBcAg by

longer N terminus and longer C terminal tail

shorter N terminus and shorter C terminal tail

shorterr N terminus and longer C terminal tail

longer N terminus and shorter C terminal tail

Q 5. false about HBsAg in acute HBV infection

precedes rise in ALT

orecedes clinical symptoms

detectable during entire icteric phase

rarely persists beyond 3 months

Q 6. following is a member of genus Deltavirus

Hepatitis D virus

Marburg virus

California encephalitis virus

all of the above

Q 7. delta core of HDV is encapsulated by an outer envelope of

HBcAg

HBsAg

HBeAg

any of the above

Q 8. false about expression of core protein and HBeAg

core protein is translated from pregenomic mRNA using the ATG codon at 1901 as initiation site

HbeAg translated from precore mRNA using ATG at 1814

G1896A nonsense mutation in precore region specifically prevents translation of HBeAg

none of the above

Q 9. following is the qualitative marker of the replicative stage of HBV infection

HBsAg

HBcAg

HBeAg

HBxAg

Q 10. replicative phase of chronic HBV infection converts to relatively non replicative phase ata rate of

10% per year

20% per year

30% per year

40% per year

Q 11. following is false about severe chronic HBV infection due to precore region HBV mutant

detectable HBV DNA

HBeAg negative

anti-HBe positive

none of the above

Q 12. HBV genotype most frequent in India

any of the above

Q 13. spontaneous reactivation of replicative HBV infection from non replicative phase is marked by which of the following

Re-expression of HBeAg

re-expression of HBV DNA

reappearance of IgM anti-HBc

all of the above

Q 14. last antibody to appear following HBV infection

Anti-HBc

Anti-HBs

Anti-HBe

none of the above

Q 15. after the onset of jaundice HBsAg rarely persists beyond how many months

1 months

3 months

6 months

9 months

Q 16. extrahepatic sites where Hepatitis B antigen and HBV DNA has been identified is

bone marrow

spleen

pancreas

all of the above

Q 17. false about delta hepatitis virus

defective RNA virus

35 to 37 nm in size

1700 nucleotide genome

has antigenic homology with HBV antigens

Q 18. false statement regarding HBV

HBeAg is not a part of the virus particle

anti-HBc antibody rises soon after infection

HBeAg expression is not essential for virus replication

none of the above

Q 19. false statement regarding serology in acute HBV infection

Anti-HBs appears after HBsAg disappears

Anti-HBs remains detectable indefinitely

Anti-HBs precedes appearance of anti HBc

HBeAg appears with HBsAg

Q 20. replicative chronic hepatitis B in the absence of HBeAg occurs in which of the following

patients with core mutations

patients with precore mutations

patients with pre S1 muttions

patients with pre S2 mutations

Q 21. recent and remote HBV infections can be distinguished by determination of

Anti-HBs

IgM anti-HBc

IgG anti-HBc

all of the above

Q 22. true regarding gap or window period in acute HBV infection

absence of HBsAg

absence of anti HBs

presence of IgM anti HBc

all of the above

Q 23. which of the following presence represents hepatitis B infection in remote past

Anti-HBc

Anti-HBs

Anti-HBe

any of the above

Q 24. following is expressed during periods of peak replication

HBeAg

pre-S1 proteins

pre-S2 proteins

all of the above

Q 25. first antibody to appear following HBV infection

Anti-HBc

Anti-HBs

Anti-HBe

none of the above

Q 26. single stranded RNA genome of HDV is homologus to an extent with which gene of HBV

Q 27. first virologic marker detectable in serum after infection with HBV

HBsAg

HBeAg

HBcAg

HBxAg

Q 28. following is false about the serology in the first stage of HBV patient

presence of HBsAg

presence of HBeAg

presence of anti-HBs antibody

presence of IgM anti HBc antibody

Q 29. following about HBeAg in acute HBV infection is false

appears with HBsAg

appearance coincides with high viral replication

ubdetectable after peak rise in ALT

undetectable after disappearance of HBsAg

Q 30. seroconversion from HBeAg positive to anti HBe positive is accompanied by which of the following

acute elevation in aminotranseferase activity

hemoglobinuria

anemia

all of the above

GASTROINTESTINAL AND LIVER DISEASE – Exercise 29

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GASTROINTESTINAL AND LIVER DISEASE – Exercise 29

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