GASTROINTESTINAL AND LIVER DISEASE – Exercise 30

The multiple choice questions in this online test paper focuses on GASTROINTESTINAL AND LIVER DISEASE MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online GASTROINTESTINAL AND LIVER DISEASE MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. in HEV gene encoding nucleocapsid protein

ORF1

ORF2

ORF3

all of the above

Q 2. which ORF in hepatitis E virus gene encodes the non structural enzymatic activities required for viral replication

ORF1

ORF2

ORF3

all of the above

Q 3. HBV infection acquired during adolescence or early adulthood is associated with all except

robust host immune response

acute hepatitis like Il28llness

failure to recover is the exception

chronicity is common

Q 4. HCV genotypes differ one from another in sequence homology by

10%

20%

30%

40%

Q 5. HDV RNA requires which of the following for its replication

Host RNA polymerase I

viral RNA polymerase I

Host RNA polymerase II

viral RNA polymerase II

Q 6. HBV infection in neonatal period is associated with all except

acquisition of immunologic tolerance to HBV

absence of acute hepatitis illness

almost invariable establishments of chronic infection

never go into cirrhosis & hepatocellular carcinoma

Q 7. folowing acts as an animal reservoir contributing to the perpetuation of HEV

swine

bird

fish

dog

Q 8. which of the following statements is false

patients with defects in cellular immune competence are more likely to remain chronically infected with HBV

chronic HBV infection can occur in the absence of serum hepatitis B e antigen (HBeAg)

most characterstic histologic feature of chronic HBV infection is ground glass hepatocyte due to intracellular accumulation of HBsAg

none of the above

Q 9. false regarding HEV

HEV replicates in cytoplasm

genotypes 1 and 2 are human viruses

genotype 3 and 4 are swine viruses

none of the above

Q 10. following is the structural gene in hepatitis C virus genome

all of the above

Q 11. following is a member of family flaviviridae

yellow fever virus

dengue virus

hepatitis c virus

all of the above

Q 12. following nonstructural regions of hepatitis C virus genome codes for RNA dependent RNA polymerase

NS3

NS4

NS5A

NS5B

Q 13. which hepatitis earlier called nonA-non B hepatitis

hepatitis A

hepatitis B

hepatitis C

hepatitis E

Q 14. false about delta virus

HDV antigen is expressed in hepatocyte nuclei

intracellular replication of HDV RNA can occur without HBV

duration of HDV infection determined by duration of HBV infection

in acute HDV infection anti HDV detected before symptoms appear

Q 15. in hepatitis c virus genome which of the following functions as an ion channel

Q 16. false regarding HEV

HEV RNA is detectable in stool guring incubation period

HEV RNA is detectable in serum during incubation period

IgM antibody is undetectable during recovery

none of the above

Q 17. following is an HDV protein

HDAg

HDsAg

HDeAg

all of the above

Q 18. ORF1 encodes which of the following nonstructural proteins

methyltranseferase

cysteine protease

helicase

all of the above

Q 19. most common cause of acute hepatitis in India

hepatitis A

hepatitis B

hepatitis C

hepatitis E

Q 20. which of the following is false about HCV

40-60 nm in diameter

9600 nucleotide RNA virus

its half life is 2.7 hours

none of the above

Q 21. HEV related to

flaviviridae

hepeviridae

rhabdoviridae

arenaviridae

Q 22. following is associated with more severe outcome of HBV infection

infection with precore genetic mutants of HBV

concomitant HDV and HBV infections

in liver transplantation for end stage chronic hepatitis B

all of the above

Q 23. HCV masquerade as which of the following

viriod

nucleocapsid protein

lipoprotein

CD81 receptor

Q 24. Epidemic non A non B hepatitis relates to which of the following

hepatitis A

hepatitis B

hepatitis C

hepatitis E

Q 25. false about HCV

HCV enters hepatocyte via CD81 receptor

HCV infection does not induce lasting immunity against reinfection

most sensitive indicator of HCV infection is the presence of HCV RNA

none of the above

Q 26. incubation period of acute hepatitis E infection is

1 to 2 weeks

2 to 4 weeks

3 to 8 weeks

6 to 12 weeks

Q 27. first detectable event during acute hepatitis C progressing to chronicity

HCV RNA

HCV DNA

elevated ALT

elevation and disappearance of anti-HCV

Q 28. false about HEV

enveloped virus

single stranded positive sense RNA genome

genome is 7.6 kb in length

genome contains three open reading frames

Q 29. following statement is false

hepatitis B virus is not directly cytopathic

HBcAg invites cytolytic T cells to destroy HBV infected hepatocytes

inactive hepatitis B carriers can have normal liver histology

none of the above

Q 30. number of HCV genotypes identified is

GASTROINTESTINAL AND LIVER DISEASE – Exercise 30

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GASTROINTESTINAL AND LIVER DISEASE – Exercise 30

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