HEMATOLOGY MCQ – Exercise 15

The multiple choice questions in this online test paper focuses on HEMATOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online HEMATOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. following gene mutations accounts for majority of autosomal dominant hereditary spherocytosis

ANK1

SPTA1

SLC4A1

EPB41

Q 2. normally what percentage of RBC precursors are destroyed in bone marrow

10-15%

25-30%

50-60%

75-80%

Q 3. normal range of cobalamin in serum is

5 to 100 ng/L

100 to 200ng/L

160 to 1000 ng/L

1000 to 2500 ng/L

Q 4. serum homocystiene raised in all except

chronic renal disease

hyperthyroidism

alcoholism

pyridoxine deficiency

Q 5. fish tapeworm- D.latum causes megaloblastic anemia due to

defective release of cobalamin from food

inadequate production of intrinsic factor

competition for cobalamin

intestinal stasis

Q 6. reticulocytosis after intramuscular cyanocobalamin therapy for megaloblastic anemia peaks at about

day 3

day 5

day 7

day 10

Q 7. better index of folate stores

serum folate stores

RBC folate level

WBC folate level

platelet folate level

Q 8. tissue folate concentration in folate deficiency due to drugs inhibiting dihydrofolate reductase are

normal

elevated

reduced

any of the above

Q 9. conditions that increases demand of folic acid are all except

chronic hemolytic anemia

pregnancy

hemodialysis

Q 10. following manifestations occur with cobalamin deficiency but not with folic acid deficiency

gastrointestinal

neurologic

hematologic

all of the above

Q 11. phospholipid of RBC membrane is

phosphatidylcholine

phosphatidylethanolamine

sphingomyelin

all of the above

Q 12. for cobalamin maintenance therapy 1000 µg of cynocobalamin im is given

once a month

once every 2 months

once every 3 months

once every 6 months

Q 13. combined deficiency of cobalamin and folic acid seen in

gastric achlorhydria

tropical sprue

regional enteritis

pregnancy

Q 14. isoenzyme of plasma lactic acid dehydrogenase is increased in enhanced intramedullary destruction of erythroblasts

isoenzyme 1

isoenzyme 2

isoenzyme 3

isoenzyme 4

Q 15. folic acid supplementation is required in patients on chronic hemodialysis because

folate is lost in dialysate

heparin reduces folate levels in blood

protamin reduces folate levels in blood

all of the above

Q 16. for cobalamin maintenance therapy 1000 µg of hydroxocobalamin im is given

once a month

once every 2 months

once every 3 months

once every 6 months

Q 17. following is raised in patients with cobalamin deficiency

calcium

iron

serum methylmalonate

glycine

Q 18. following is given in megaloblastic anemia due to folate antagonists

folic acid

folinic acid

pyridoxine

all of the above

Q 19. malabsorption of folate seen with following drug intake

salazopyrine

cholestyramine

triameterene

all of the above

Q 20. oral dose of folic acid in folate deficiency is

5-15 mg for 1 month

5-15 mg for 4 months

5-15 mg for 8 months

5-15 mg for 12 months

Q 21. largest component of RBC membrane

protein

lipid

carbohydrate

others

Q 22. normal range of serum folate is

2 to 15 µg/L

12 to 25 µg/L

25 to 45 µg/L

42 to 75 µg/L

Q 23. false regarding cobalamin

cobalamin is an essential cofactor for methionine synthase and methylmalonyl CoA synthase

methylcobalamin and adenosylcobalamin are metabolically active forms

therapeutically available as cyanocobalamin

cyanocobalamin is biologically active

Q 24. alcohol causes folic acid deficiency by

inadequate intake

increased requirements

malabsorption

impaired metabolism

Q 25. folate deficiency occurs in

sickle cell disease

AIHA

congenital spherocytosis

all of the above

Q 26. acute megaloblastic anemia can occur after

nitrous oxide anesthesia

halothane anesthesia

chloroform anesthesia

ether anesthesia

Q 27. main cytoskeletal protein is

band 3

band 4.1

glycophorin

spectrin

Q 28. enzyme required for the production and utilization of ATP in RBC cell membrane is

aldolase

glyceraldehydes 3 phosphate dehydrogenase

phosphoglycerate kinase

all of the above

Q 29. cobalamin deficiency without anemia is common in

infants

adolescent

adults

elderly

Q 30. neonatal folate level falls rapidly to the lowest values at

6 weeks of age

12 weeks of age

24 weeks of age

32 weeks of age

HEMATOLOGY MCQ – Exercise 15

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HEMATOLOGY MCQ – Exercise 15

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