HEMATOLOGY MCQ – Exercise 7

The multiple choice questions in this online test paper focuses on HEMATOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online HEMATOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. neutrophils normally spend how much time in circulation

2 to 3 hours

6 to 7 hours

12 to 24 hours

24 to 36 hours

Q 2. Rolling of the neutrophil along the endothelial surface is a function of

selectins

integrins

intercellular adhesion molecules

opsonins

Q 3. false regarding LAD 1 and 2

autosomal dominant traits

inability of neutrophils to exit circulation

leucocytosis

increased susceptibility to infection

Q 4. congenital forms of Neutropenia include

Kostmann’s syndrome

Shwachman-Diamond syndrome

WHIM syndrome

all of the above

Q 5. inflammatory process is absent when absolute neutrophil count falls below

<100 cells/µL

<200 cells/µL

<500 cells/µL

<1000 cells/µL

Q 6. characteristic green colour to pus is due to

collagenase

elastase

myeloperoxidase

all of the above

Q 7. for lymphocyte CD stands for

clonal determinant

cluster determinant

capsule determinant

cell development

Q 8. senescent neutrophils are cleared from the circulation by macrophages in

kidneys

lung

GI tract

thymus

Q 9. in severe acute bacterial infections following is seen in neutrophils

toxic granulations

Dohle bodies

large neutrophil vacuoles

all of the above

Q 10. Neutropenia can be due to

decreased production

increased peripheral circulation

excessive peripheral pooling

all of the above

Q 11. not a group of chemokines

CCC

CXC

Q 12. pancreatic insufficiency seen in

Kostmann’s syndrome

Shwachman-Diamond syndrome

WHIM syndrome

all of the above

Q 13. susceptibility to infectious diseases increases sharply when neutrophil counts fall below

1000 cells/µL

2000 cells/µL

3000 cells/µL

4000 cells/µL

Q 14. congenital disorder of glycosylation IIc includes

LAD1

LAD2

LAD3

none of the above

Q 15. neutrophilia results from

increased neutrophil production

increased marrow release

defective margination

all of the above

Q 16. neutrophils stick to the endothelium through

selectins

integrins

intercellular adhesion molecules

opsonins

Q 17. neutrophilia caused by

meprobamate

lithium

phenothiazines

phenylbutazone

Q 18. in the healthy adult most neutrophils leaves the body by

migration through mucous membrane of GI tract

apoptosis

phagocytosis

all of the above

Q 19. drugs causing Neutropenia due to decreased production

carbamazepine

clozapine

antithyroid drugs

all of the above

Q 20. transient Neutropenia due to peripheral pooling occurs in

acute endotoxemia

hemodialysis

cardiopulmonary bypass

all of the above

Q 21. diapedesis involves

PECAM1

anaphylaxis

VEGF

PG E and I

Q 22. drugs acting as haptens to cause Neutropenia due to peripheral destruction

alpha methyldopa

phenylbutazone

mercurical diuretics

all of the above

Q 23. persistent neutrophilia with cell counts of what level is called leukemoid reaction

> 10000 to 30,000 /µL

> 30000 to 50,000 /µL

> 50000 to 75,000 /µL

> 75000 to 100,000 /µL

Q 24. percentage of neutrophil pool in the circulation under normal condition

~2%

~20%

~50%

~90%

Q 25. patients with LAD1 have mutations in

CD 18

CD 31

CD 34

CD 62

Q 26. Kostmann’s syndrome is due to mutations in

potassium voltage gated channel gene KCNA1

PKD-1 gene

anti-apoptosis gene HAX-1

GJB2 gene

Q 27. regarding Dohle body true statement includes

discrete blue staining non granular areas found in periphery of cytoplasm of neutrophils

found in infections and other toxic states

aggregates of rough endoplasmic reticulum

all of the above

Q 28. marginated leukocytes are maximum in

lungs

spleen

liver

kidneys

Q 29. true regarding leukemoid reaction

neutrophil cell count > 30000 to 50,000 /µL

Circulating neutrophils are mature

circulating neutrophils are clonally derived

all of the above

Q 30. Felty’s syndrome include all except

rheumatoid arthritis

hepatomegaly

splenomegaly

neutropenia

HEMATOLOGY MCQ – Exercise 7

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