NEUROLOGY MCQ – Exercise 57

The multiple choice questions in this online test paper focuses on NEUROLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online NEUROLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. in seronegative myasthenia gravis antibodies can be found against

muscle specific tyrosine kinase

myasthenic specific tyrosine kinase

membrane specific tyrosine kinase

all of the above

Q 2. myasthenia gravis includes all except

acetylcholine is released normally

decrease in number of available Ach receptors

increased presynaptic rundown

thymus abnormal in ~ 75% of patients

Q 3. true regarding anti-MuSK antibodies

found in ~ 40% of AChR antibody negative generalized myasthenia gravis

not present in AChR antibody positive generalized myasthenia gravis

not present in myasthenia gravis limited to ocular muscles

all of the above

Q 4. pathogenic anti-AChR antibody in myasthenia gravis is

IgA

IgG

IgM

IgE

Q 5. false positive edrophonium anticholinesterase test is seen in

amyotrophic lateral sclerosis

Hodgkin lymphoma

Charcot-Marie –Tooth disease

Creutzfeldt-Jakob disease

Q 6. other than edrophonium which drug can be used for anticholinesterase test

atropine

neostigmine

adrenaline

all of the above

Q 7. anti-MuSK antibodies are found in what percentage of AChR antibody positive patients with generalized myasthenia gravis

rare

~40%

~80%

~100%

Q 8. which drug should be kept ready at hand while conducting edrophonium anticholinesterase test

atropine

neostigmine

adrenaline

all of the above

Q 9. in congenital myasthenic syndromes what component of the neuromuscular junction may be affected

presynaptic nerve terminal

various subunits of AChR

various subunits of AChE

all of the above

Q 10. anti-MuSK antibodies are found in what percentage of patients with myasthenia gravis limited to ocular muscles

rare

~40%

~80%

~100%

Q 11. in myasthenia gravis which of the following spirometric parameter is false

normal FRC

low TLC

elevated RV

normal FVC

Q 12. which type of respiratory failure occurs in myasthenia gravis

type1

type2

type3

type4

Q 13. myasthenia gravis may be induced by

pencillamine

aminoglycoside antibiotics

procainamide

diazepam

Q 14. fluctuating ptosis that worsens late in the day is indicative of

myasthenia gravis

glaucoma

optic nerve glioma

orbital cellulitis

Q 15. in myasthenia gravis if muscle weakness remains restricted to extraocular muscles for how much time it will not become generalized

6 months

2 year

3 years

4 years

Q 16. in myasthenia gravis all are true except

women are more affected than men

deep tendon reflexes are diminished

lids and extraocular muscles involved early

limb weakness is proximal and asymmetric

Q 17. cause of episodic generalized weakness

hypokalemia , hyperkalemia , hypercalcemia

hypernatremia,hyponatremia , hypophosphatemia

myasthenia gravis , Lambert Eaton myasthenic syndrome,multiple sclerosis

all of the above

Q 18. in repetitive nerve stimulation for evidence of myasthenia gravis which muscle group is best to test

proximal muscle groups

distal muscle groups

interosseous muscles

any of the above

Q 19. in myasthenic patients rapid reduction of what proportion in amplitude of evoked response is noted

>10-15%

>20-30%

>30-45%

>50-75%

Q 20. myasthenia gravis is related to

neuromyelitis optica

M component on electrophoretic analysis

hyperthyroidism

all of the above

Q 21. myasthenia gravis includes

no loss of reflexes

no impairment of sensation

no HMF neurologic deficit

all of the above

Q 22. congenital myasthenic syndromes include all except

due to genetic mutations

α subunit of AChR is affected in ~75% of patients

AChR antibody tests are consistently negative

symptoms begin in infancy or childhood

Q 23. thymoma and or myasthenia gravis is associated with

pemphigus vulgaris

pemphigus foliaceus

paraneoplastic pemphigus

bullous pemphigoid

Q 24. in myasthenia gravis autoimmune antibody is targeted against

acetylcholine

ACh receptor

acetylcholinesterase

all of the above

Q 25. anti-MuSK antibodies are found in what percentage of AChR antibody negative patients with generalized myasthenia gravis

~10%

~40%

~80%

~100%

Q 26. Good`s syndrome associated with thymoma and

hypogammaglobulinemia

pure red cell aplasia

SLE

ulcerative colitis

Q 27. in myasthenia gravis if muscle weakness remains restricted to extraocular muscles for how much time it will not become generalized

6 months

2 year

3 years

4 years

Q 28. drugs that can exacerbate myasthenia gravis weakness includes all except

aminoglycosides

quinolones

macrolides

procainamide

Q 29. in myasthenia gravis anti-Ach recptor antibodies reduce the number of available AChRs at NMJ by

endocytosis of the receptors

blockade of the active site of AChR

damage to the post synaptic muscle membrane

all of the above

Q 30. anti-AChR antibodies are detectable in what percentage of myasthenic gravis and ocular myasthenic gravis patients respectively

85% and 80% respectively

80 and 85% respectively

85% and 50% respectively

50% and 85% respectively

NEUROLOGY MCQ – Exercise 57

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NEUROLOGY MCQ – Exercise 57

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