ENDOCRINOLOGY MCQs – Exercise 5

The multiple choice questions in this online test paper focuses on ENDOCRINOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online ENDOCRINOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. most common cause of GHRH- mediated acromegaly is

pancreatic islet cell tumor

pheochromocytoma

abdominal carcinoid tumor

medullary thyroid carcinoma

Q 2. in ACTH deficiency, total daily dose of hydrocortisone replacement therapy should not exceed

10 mg daily

20 mg daily

25 mg daily

40 mg daily

Q 3. regarding Laron syndrome all are true except

GH insensitivity

normal or high GH levels

decreased circulating GHBP

high IGF-I levels

Q 4. characteristic voice in isolated GH deficiency is

high pitched

low pitched

hoarse

any of the above

Q 5. final height of children can be predicted by

Bayley-Pinneau scale

Tanner-Whitehouse scale

midparental scale

all of the above

Q 6. peak ACTH secretion occurs at

4 AM

6 AM

8 AM

10 AM

Q 7. adult GH deficiency is defined by a peak GH response to hypoglycemia of

<3 µg/L

<5 µg/L

<7 µg/L

<9 µg/L

Q 8. receptor for ACTH is

melanocortin-1 receptor

melanocortin-2 receptor

melanocortin-3 receptor

melanocortin-4 receptor

Q 9. regarding octreotide all are true except

synthetic somatostatin analogue

40 times more potent than native somatostatin

administered subcutaneously

none of the above

Q 10. besides ACTH , POMC precursor protein produces

β-lipotropin

β-endorphin

met-enkephalin

all of the above

Q 11. treatment with IGF-I is recommended for

turner syndrome

chronic renal failure

growth retardation due to mutations of GH receptor

all of the above

Q 12. what percentage of pituitary cell population are ACTH secreting corticotrope cells

~10%

~20%

~30%

~40%

Q 13. POMC gene is induced by

CRH

AVP

IL-6

all of the above

Q 14. last hormone to be lost in acquired pituitary hormone deficiency

TSH

ACTH

FSH/LH

Q 15. mammosomatotrope pituitary adenoma can lead to

hypogonadism

galactorrhea

acromegaly

all of the above

Q 16. following provocative stimuli, GH levels normally increase to how much in children

>3µg/L

>5µg/L

>7µg/L

>9µg/L

Q 17. acromegaly is associated with increased risk of which malignancy

pancreatic

colonic

breast

thyroid

Q 18. acidophil stem cell pituitary adenoma can lead to

hypogonadism

galactorrhea

acromegaly

all of the above

Q 19. following act by antagonizing endogenous GH binding to its receptor

cabergolline

lanreotide

octreotide acetate

pegvisomant

Q 20. normal daytime circulating levels of GH is

<.2 µg/L

<.3 µg/L

<.4 µg/L

<.5 µg/L

Q 21. measurement of which of the following is most useful for the diagnosis of acromegaly

GHRH

IGF-I

IGF-II

Q 22. familial modes of inheritance of isolated GH deficiency is

autosomal dominant

autosomal recessive

X-linked

any of the above

Q 23. in acromegaly, following oral glucose load, GH levels remain more than

>.1 µg/L

>.2 µg/L

>.3 µg/L

>.4 µg/L

Q 24. ACTH levels are increased by

AVP

physical stress

insulin induced hypoglycemia

all of the above

Q 25. organ not enlarged in acromegaly

tongue and liver

thyroid gland and kidney

parotid gland and pancreas

heart and prostate

Q 26. regarding acromegaly all are true except

often clinically not diagnosed for 10 years or more

without treatment survival is reduced by ~10 years

hypertension occur in about 75% of patients

diabetes mellitus develops in 25% of patients

Q 27. contraindication to GH therapy includes

presence of active neoplasm

intracranial hypertension

uncontrolled diabetes

all of the above

Q 28. side effect of octreotide

tachcardia

cholesterol gallstones

hypoglycemia

all of the above

Q 29. in GH microadenomas which is the preferred primary treatment

surgical resection

somatostatin analogues

dopamine agonists

irradiation

Q 30. prognathism is due to enlargement of

maxilla

mandible

nasal bones

all of the above

ENDOCRINOLOGY MCQs – Exercise 5

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