ENDOCRINOLOGY MCQs – Exercise 27

The multiple choice questions in this online test paper focuses on ENDOCRINOLOGY MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online ENDOCRINOLOGY MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. testosterone is metabolized predominantly in

liver

skeletal muscle

prostate

skin

Q 2. true statement includes

LH acts on leyding cells to stimulate testosterone synthesis

FSH acts on sertoli cells to regulate spermatogenesis

inhibin B is produced by seroli cells

all of the above

Q 3. pregnenolone is formed from cholesterol through cleavage by

CYP17

CYP11A1

CYP19

17β hydroxysteroid dehydrogenase

Q 4. StAR stands for

Steroid active regulatory proteins

steroid associated regulatory proteins

steroid acute regulatory proteins

steroid amplifying regulatory proteins

Q 5. regarding androgen receptor true statement includes

distributed in both cytoplasm and nucleus

is a ligand regulated transcription factor

testosterone binds to AR with half the affinity of DHT

all of the above

Q 6. following acts as a catalyst

CYP17

CYP11A1

CYP19

17β hydroxysteroid dehydrogenase

Q 7. percentage of unbound testosterone

.5 to 3%

5 to 8%

11 to 13%

15 to 30%

Q 8. what is approximately total length of seminiferous tubules which form approximately two third of testis volume

100 meters

200 meters

400 meters

600 meters

Q 9. number of carbon atoms in a cholesterol molecule is

Q 10. which of the following is converted by 17 β-HSD3 to testosterone

pregnenolone

progesterone

androstenedione

17-OH progesterone

Q 11. true statement includes

most circulating DHT comes from peripheral conversion of testosterone

a small amount of DHT is secreted directly by testis

in men daily production of estradiol comes from peripheral conversion of testosterone and androstenedione

all of the above

Q 12. daily testicular secretion of circulating testosterone is

3 to 10 mg/day

8 to 20 mg/day

13 to 30 mg/day

20 to 40 mg/day

Q 13. in liver testosterone is converted enzymatically to all except

androsterone

androstenedione

DHT

3α-androstanediol

Q 14. primary spermatocytes are derived from

type A spermatogonia

type B spermatogonia

type C spermatogonia

type D spermatogonia

Q 15. in normal men , LH released in discrete pulses approximately every

half to 1 hour

1 to 3 hours

3 to 4 hours

4 to 6 hours

Q 16. which of the following is true statement

advanced age does not influence testicular size

varicocele is more common on left side

in klinefelter syndrome testicular volume is markedly reduced

all of the above

Q 17. normal adult testes produce approximately how many sperms per day

25 million

50 million

75 million

100 million

Q 18. regarding spermiogenesis all are true except

chromatin condensation

shedding of an acrosome

elongation of cytoplasm

formation of tail

Q 19. androgen receptor is encoded by a gene located on

short arm of X chromosome

long arm of X chromosome

short arm of chromosome 6

long arm of X chromosome 7

Q 20. in males , growth spurt occurs at a testicular volume of

4 to 6 mL

6 to 10 mL

10 to 12 mL

15 to 20 mL

Q 21. which type of spermatogonia serves as stem cells capable of self renewal

type A spermatogonia

type B spermatogonia

type C spermatogonia

type D spermatogonia

Q 22. formation of mature spermatozoa from germ cells takes about

24 days

44 days

74 days

94 days

Q 23. sex hormone binding globulin concentrations are increased by all except

estrogen administration

hyperthyroidism

insulin

aging

Q 24. severe male factor infertility has sperm count of

<10 ×106/mL and 40% motility

<10×106/mL and 30% motility

<10×106/mL and 20% motility

<10×106/mL and 10% motility

Q 25. androgen receptor is structurally related to the nuclear receptors for

estrogen

glucocorticoids

progesterone

all of the above

Q 26. testosterone is converted to DHT by

5α-reductase

17 α-reductase

17β-hydroxysteroid dehydrogenase 2

17 β-hydroxysteroid dehydrogenase 3

Q 27. how many major enzymatic steps are involved in in testosterone synthesis from cholesterol?

Q 28. mild male factor infertility have sperm count of

5-10 ×106/mL and normal motility

10-15×106/mL and normal motility

15-20×106/mL and normal motility

20-25×106/mL and normal motility

Q 29. hypothalamic GnRH released in discrete pulses approximately every

1 hour

2 hours

3 hours

4 hours

Q 30. sex hormone binding globulin concentrations are decreased by all except

androgens

obesity

hyperthyroidism

nephritic syndrome

ENDOCRINOLOGY MCQs – Exercise 27

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