Reproductive Biology / Medicine / Infertility MCQs – Exercise 10

The multiple choice questions in this online test paper focuses on Reproductive Biology / Reproductive Medicine / Infertility MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online Reproductive Biology / Reproductive Medicine / Infertility MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. False regarding the progestin containing IUD

It disrupts endometrial maturation and creates environment hostile for implantation.

Risk of ectopic pregnancy greater with the IUD than using no contraception use.

It does not abort a successfully implanted pregnancy

It is associated with less bleeding than Cu IUD device.

Q 2. Antiphosopholipid-related nephropathy is characterized by presence of renal biopsy findings of:

WHO class IV glomerulonephritis

Necrotizing vacuities

Thrombotic microangiopathy with glomerular thrombi and atrophy

Amyloid deposition

Q 3. 2. The international consensus statement on classification criteria for antiphospholipid syndrome (“Sapporo criteria”) includes laboratory and clinical criteria. Clinical criteria include:

Vasculitis or pregnancy loss only

Arterial or venous thrombosis only

Thrombocytopenia, thrombosis, and pregnancy loss or pre-eclampsia

Vascular thrombosis or pregnancy morbidity, including recurrent early losses, late loss, or premature births due to severe pre-eclampsia or severe placental insufficiency

Q 4. Autoimmune antiphospholipid antibodies:

Represent a spectrum of auto antibodies directed at phospholipid-binding plasma proteins

Represent a spectrum of antibodies directed specifically at cardiolipin only

Interfere with hemostasis by increasing plasma levels of prothrombin

Represent an autosomal recessive genetic disorder due to a single gene mutation

Q 5. Hematologic manifestations associated with APS include:

Thrombocytopenia, Coombs positive hemolytic anemia, and thrombotic microangiopathic hemolytic anemia

Thrombocythemia

Thrombocytopenia only

Thrombocytopenia with bone marrow fibrosis

Q 6. Antiphospholipid syndrome is diagnosed by the presence of anticardiolipin antibodies and is characterized by:

infection

thrombosis

joint deformity

systemic sclerosis

Q 7. OCPs prevents pregnancy by all except

Inhibition of ovulation.

Thickening of cervical mucus to prevent sperm transport.

Creating a local inflammatory response in the endometrium with release of excess Prostaglandins.

prevent implantation of fertilized egg by alteration in endometrium

Q 8. Following is not a manifestation of antiphospholipid syndrome:

Hyperlipedemia

Pulmonary hypertension

Recurrent abortions

Deep vein thrombosis

Q 9. Which is thought to increase likelihood of thrombosis in an aPL (+) individual, in keeping with the “second hit” hypothesis?

Inherited thrombophilia such as factor V Leiden

Oral contraceptives

Prolonged immobilization

All of the above

Q 10. Acquired hrombophilia include all except

Antiphospholipid antibody syndrome

HIT

PNH

Protein S deficiency

Q 11. Antiphospholipid antibody syndrome include all except

Pregnancy loss ≥ 3 at less than 10 weeks gestation period.

≥ 1 loss of morphologically fetus after 10 weeks.

≥ 1 premature birth of neonate before 34 weeks because of pre eclampsia/eclampsia

More than 2 neonatal deaths due to idiopathic reason.

Q 12. Regarding sterilization true includes

Failure rate is zero if properly performed

Tran cervical sterilization involves placement of micro inserts using a hysteroscope.

Tubal reanastomosis results in post procedure 10% pregnancy rate.

The risk of ectopic pregnancy is 10% if pregnancy occurs post ligation.

Q 13. The contraceptive implant containing progestin, which is slowly released over a period of up to 5 years

RU-486

Depo-Provera

Norplant

Nonoxynol-9

Q 14. Mainstay of treatment of antiphospholipid syndrome is:

Statins

Warfarin

Ecospirin

Corticosteroids

Q 15. 1. The international consensus statement on classification criteria for antiphospholipid syndrome (Sapporo criteria) includes laboratory and clinical criteria. The laboratory criteria include:

Any antiphospholipid antibody documented by ELISA

Moderate to high titer IgG, IgM, or IgA anticardiolipin antibody only

Moderate to high titer IgG or IgM anticardiolipin antibody or positive lupus anticoagulant

Biologic false positive serologic test for syphilis and lupus anticoagulan

Q 16. Most commonly seen antibody in antiphospholipid antibody syndrome?

Anti beta 2 glycoprotein antibody

Anti nuclear antibody

Anti centromere antibody

Beta 2 micro globulin antibody

Q 17. regarding Laboratory criteria in the antiphospholipid syndrome, one of the following is correct:

Medium/high titre of IgG and/or IgM isotype anticardiolipin antibody in blood on 2 or more occasions at least 2 weeks apart using standard assays

Lupus anticoagulant present in plasma on 2 or more occasions at least 3 weeks apart.

Lupus anticoagulant present in plasma on 2 or more occasions at least 6 weeks apart

None

Q 18. a person had a vasectomy three weeks ago. This means that he:

can have unprotected intercourse and not worry about a pregnancy because he is no longer fertile.

could still be fertile and needs to wait a few weeks before depending on his vasectomy for contraception.

will have a more watery ejaculate than he had before

will not have any ejaculate when he has an orgasm

Q 19. The most common presentation of arterial thrombosis in antiphospholipid syndrome (APS) patients is:

Aortic occlusion

Stroke and transient ischemic attack

Digital gangrene

Renal artery thrombosis

Q 20. Regarding miscarriages

Commonest cause of sporadic miscarriage is chromosomal abnormality.

Risk of miscarriages increases with age.

outcome of pregnancy in woman with antiphoshpholipid syndrome significantly improves with aspirin and warfarin.

outcome of pregnancy in woman with antiphoshpholipid syndrome significantly improves with aspirin and heparin.

Q 21. How does a diaphragm with spermicide work?

It pushes sperm outside the vagina

It prevents an egg from being released by the ovary

It both kills and prevents sperm from entering the cervix

It prevents eggs from entering the uterus

Q 22. Treatments for antiphospholipid syndrome include

Anti platelet agents

Anti coagulants

immunosuppressive therapy

All

Q 23. Laboratory criteria for antiphoshpholipid syndrome includes

Lupus anticoagulant present on two or more occasions at least 12 week apart.

Anticardiolipin antibody of IgG or IgM isotype in medium to high titer on on two or more occasions at least 12 week apart

Anti-β2-glycoproein 1 antibody of IgG or IgM isotype in 99th percentile titer on on two or more occasions at least 12 week apart

all true

Q 24. A patient with recurrent DVTs ,miscarriages and raynaud phenomenonlikel has

SLE

Giant cell arteritis

Rheumatoid arthritis

Antiphospholipid antibody syndrome

Q 25. The most common cardiac manifestation of APS is:

Atrial thrombus

Valvular heart disease, especially aortic and mitral regurgitation

Thrombotic cardiomyopathy

Restrictive cardiomyopathy

Q 26. Which of the following statements regarding treatment of APS manifestations is false?

No prospective data exist to support prophylactic treatment of asymptomatic aPL(+) patients, but high titer patients are often treated with low-dose aspirin

Standard treatment of a single arterial thrombosis is anticoagulation with aspirin 325 mg in combination with warfarin at an INR of 3.5-4.0

Standard treatment of recurrent pregnancy loss associated with aPL is low-dose aspirin and a prophylactic dose of subcutaneous heparin

Precise type, duration, and intensity of anticoagulation is still in question for many patients with aPL-related thromboses

Q 27. Which of the following statements regarding obstetric complications of APS is false?

The two greatest risk factors for fetal loss are high titer IgG anticardiolipin (aCL) and a history of prior fetal loss.

Obstetric complications may include early severe pre-eclampsia and/or HELLP syndrome.

Screening of every pregnant woman for aCL and lupus anticoagulant (LA), regardless of obstetric history, is now recommended.

Concordance of aCL and LA tests are incomplete, so both must be checked if APS is suspected

Q 28. The antiphospholipid syndrome:

Some healthy individuals have antiphospholipid antibodies without symptoms.

Fewer than 20 per cent of babies are born alive to mothers with untreated Antiphospholipid syndrome.

Is characterized by high levels of anticardiolipin antibodies.

In labour, patients who regularly took 7.5 mg or more of prednisolone per day during the fortnight before delivery should continue on this dose.

Q 29. The health risks of taking the birth control pill are increased if the woman:

Overweight

Smokes

Has low blood pressure

Has heavy periods

Q 30. regarding Vascular thrombosis criteria in the antiphospholipid syndrome:

1 or more episodes of arterial, venous or small vessel thrombosis in any tissue or organ confirmed with imaging or histopathology

1 or more episodes of arterial, venous or small vessel thrombosis in the abdomen confirmed with imaging or histopathology

1 or more episodes of superficial venous thrombosis and any arterial, venous or small vessel thrombosis in any tissue or organ

2 or more episodes of arterial, venous or small vessel thrombosis in the abdomen confirmed with imaging or histopathology.

Reproductive Biology / Medicine / Infertility MCQs – Exercise 10

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Reproductive Biology / Medicine / Infertility MCQs – Exercise 10

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