Reproductive Biology / Medicine / Infertility MCQs – Exercise 13

The multiple choice questions in this online test paper focuses on Reproductive Biology / Reproductive Medicine / Infertility MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online Reproductive Biology / Reproductive Medicine / Infertility MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. Most common primary pituitary cause of hyperprolactinemia

Cushing disease

Prolactin secreting adenoma

Acromegaly

Non secreting adenoma

Q 2. In PCOS of 27 year patient with morbid obesity, lower abdominal and facial hair and Acne. Mechanism least likely to be involved in her case

Hyperandrogenism causing local follicular arrest and anovulation.

Increased somatotropic activity due to exaggerated growth hormone pulse amplitude

Defects in insulin signaling for glucose transport and lipolysis

Insulin and LH worling synergistically in a stimulatory fashion on thecal cells.

Q 3. Which of these statements is true with regard to bromocriptine?

It is a dopamine antagonist

Effect of bromocriptine on plasma prolactin is short-lived, lasting for 8-12 hours

Half-life of bromocriptine is 36 hours

Bromocriptine appears to be teratogenic

Q 4. Which of these statements is not true with regard to pregnancy and prolactin?secreting pituitary tumor?

There is risk of expansion of pituitary tumor during pregnancy

Pregnancy should be terminated.

In case of microprolactinoma, medical therapy should be stopped as soon as pregnancy is confirmed

Periodic checking of prolactin is of no benefit

Q 5. Long term effects of hyperprolactinemia are:

Osteoporosis

Ischemic heart disease

None of the above

Both of above

Q 6. True about the regulation of prolactin secretion

Oestrogen stimulates prolactin secretion.

Negative feedback from target organs leads to decreased prolactin secretion.

Dopamine stimulates prolactin secretion

Thyrotropin releasing hormone inhibits prolactin secretion

Q 7. Dose of cabergoline for prevention of lactation is:

Single dose of 1.0mg given as soon as possible

Single dose of 2.0mg given as soon as possible

1.0 mg given once in the morning and once in the evening

2.0 mg given once in the morning and once in the evening

Q 8. Which of the following increase prolactin secretion

VIP

Angiotensin II

Serotonin

all

Q 9. The proportion of testicular volume comprised of seminiferous tubules in the human testis is:

5%.

10% to 20%.

50% to 60%.

70% to 80%.

Q 10. Which hormones play a central role in regulation of Sertoli cell function?

LH, FSH

FSH, estradiol

Prolactin, LH

FSH, testosterone

Q 11. Embryologically, the vas deferens and body of the epididymis are derived from what developmental structure?

Müllerian ducts

Wolffian ducts

Urogenital ridge

Gubernaculum testis

Q 12. A 30 year old female presented with secondary amenorrhea for 3 years along with Galactorrhea. Most likely cause of her symptoms would be

Craniopharyngioma

Prolactinoma

Meningoma

Sub arachnoid hemorrhage

Q 13. The majority of the fluid in the male ejaculate is derived from:

the epididymides.

the ejaculatory ducts.

the seminal vesicles.

the prostate.

Q 14. Which neurotransmitter functions as a physiologic inhibitor of prolactin?

Dopamine

Adrenaline

Serotonin

Acetylcholine

Q 15. A 20 year old sexually active female no vaginal bleeding since last 6 months present now with obesity, galactorrhea, hair growth on her chin. First diagnosis is

Hypothyroidism

Androgen secreting tumor

Pituitary adenoma

Pregnancy

Q 16. Which of the following inhibit prolactin secretion

VIP

Angiotensin II

Serotonin

GABA

Q 17. Which of these is not an indication for surgery for prolactin secreting pituitary tumor?

Women who have a micro adenoma, desire pregnancy, and cannot tolerate medical therapy

Patientrs who do not wish to take medical therapy for long-term

Patients who show progression after an initial response to medical therapy

First line of treatment for macroprolactinemia

Q 18. Regarding amenorrhea seen with hypothyroidism all true except

Thyroxine increases estrogen and progesterone secretion by granulose cells so thyroxine Deficiency leads to decrease production of the hormones.

Increased prolactin secretion inhibits pulsatile GnRH secretion

Thyrotropin releasing factor secretion is increased and leads to elevated prolactin Secretion.

Exaggerated pulsatile GnRH secretion causes elevated LH and an increased LH/FSH ratio.

Q 19. Asymptomatic hyperprolactinemia requires

Regular measurement of prolactin levels.

Dopamine agonist therapy.

Surgery.

None of the above.

Q 20. Which of these symptoms is rarely encountered in men with hyperprolactinemia?

Decreased libido

Erectile dysfunction

Oligospermia

Galactorrhoea

Q 21. Percentage of secondary amenorrhea due to premature ovarian failure

10%

30%

50%

Q 22. Which of these pharmacological agents does not induce hyperventilation?

Neuroleptics

Antidepressants

Dopamine agonist

Metaclopramide

Q 23. Dosage of cabergoline for management of hyperprolactinemia is:

0.5-1.0 mg once daily

0.5-1.0 mg twice daily

0.5-1.0 mg twice weekly

0.5-1.0 mg on alternate day

Q 24. all associated with increased prolactin secretion except

Sleep

Exercise

Luteal phase of the menstrual cycle

pituitary infarct

Q 25. Macroprolactinemia refers to:

A large pituitary tumor >10mm in diameter

A polymeric form of prolactin in which several prolactin molecules form a polymer

Macroprolactinoma

Prolactin level >500 µg/l

Q 26. Which of these disorders does not increase the risk of hyperprolactinemia?

Hyperthyroidism

Hypothyroidism

Chronic renal failure

Liver cirrhosis

Q 27. Which of these symptoms are not seen in females with hyperprolactinemia?

Infertility

Galactorrhoea

Menstrual irregularities

Hirsuitism

Q 28. Prolactin level should be measured in the:

Morning

Night

After meal

Anytime

Q 29. If a patient with only mildly elevated serum prolactin level has a pituitary macroadenoma, the diagnosis is more likely to be:

Non-prolactin secreting pituitary adenoma

Prolactin secreting pituitary adenoma

Any of the above

None of the above

Q 30. Regarding hyperprolcatinemic amenorrheic females

all will experience galactorrhoea

hot flashes due to their hypoestrogenic state

Anesthetic agents commonly include medications that upregulate dopamine secretion and thus lead to elevated prolactin secretion

Of all the physiological hyperprolactinemic states only lactation is assoaciated with amenorrhoea

Reproductive Biology / Medicine / Infertility MCQs – Exercise 13

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Reproductive Biology / Medicine / Infertility MCQs – Exercise 13

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