Reproductive Biology / Medicine / Infertility MCQs – Exercise 21

The multiple choice questions in this online test paper focuses on Reproductive Biology / Reproductive Medicine / Infertility MCQ. If you are looking for self evaluation of your PG Medical entrance exam preparation then this online Reproductive Biology / Reproductive Medicine / Infertility MCQ Test Paper will help you to evaluate your exam preparation.

Instruction for REPRODUCTIVE BIOLOGY/ REPRODUCTIVE MEDICINE / INFERTILITY MCQs:

1- This online MCQ practice test paper contains 30 questions.
2- Each question in this online practice test paper have four options and only 1 option is correct.
3- You can view the answers of this practice test paper after submitting the practice test paper.
Note: The answers mentioned at the end of practice test are the best suitable option as per our knowledge. Users shall cross-check the answers with their textbooks.

Q 1. Which of the following factors is a poor prognostic indicator for “METASTATIC GESTATIONAL TROPHOBLASTIC DISEASE”?

Lung metastasis

Patient age is 35 yrs

Diagnosis of disease at 6 weeks post partum

Presence of a fetus

Q 2. For bladder emptying

Detrusor contraction needed

Detrusor relaxation needed

none of these

Q 3. Correct statement regarding lower urinary tract function in MS is

Most patients with a postvoid residual report a sensation of incomplete emptying.

It is contraindicated to prescribe anticholinergics in a patient with a postvoid residual.

Detrusor sphincter dyssynergia (DSD) results in decreased bladder pressures.

DSD and impaired detrusor contraction can result in a high postvoid residual.

Q 4. Saddle anesthesia is characteristic of which of the following conditions below?

Spinal arachnoiditis.

Lesions of the centrally lying roots within the cauda equina.

Bilateral S1 radiculopathies.

Pelvic nerve injury

Q 5. Five-year survival rates of patients with low-risk, non-metastatic gestational trophoblastic disease approaches ?

100%

75%

50%

25%

Q 6. A woman experiencing a molar pregnancy has an increased risk of which of the following in subsequent gestations

Stillbirth

Prematurity

Congenital malformations

Recurrent molar gestation

Q 7. Gestational trophoblastic neoplasia false statement include

Incomplete moles are more likely to undergo malignant change than the complete moles

GTD is almost always completely curable with preservation of fertility

Lymphnode involvement is a rare feature of choriocarcinoma

GTD usually shows low resistance blood flow

Q 8. Not true regarding female sex chromosome

Each female somatic cell contains two X chromosomes

One sex chromosome becomes functionally active

functionally inactive sex chromosome condenses to appear as bar body

All the somatic cells in adult female contain an active X chromosome of maternal origin.

Q 9. Primordial follicle development completed at

8 weeks of gestation

12 weeks of gestation

16 weeks of gestation

20 weeks of gestation

Q 10. In relation to female sexual function, which of the following statements is true?

Nitric oxide-mediated vasoconstriction results in venous engorgement and swelling of the vaginal tissues.

Secretions from the cervix are the primary source of vaginal lubrication during sexual activity.

The clitoris has a density of innervation almost equivalent to the glans penis.

The bulbocavernosus clitoral reflex results in a phasic contraction of the introital and pelvic floor musculature.

Q 11. Regarding GTN false statement include

uterus is usually enlarged

Severe vomiting may occur

Hyperthyroidism may occur

Vaginal bleeding uncommon

Q 12. True statement regarding GTN

Most common site of metastasis is lung

none of the above

Q 13. A woman with a complete mole is most likely to present with which of the symptoms ?

Vaginal Bleeding

Excessive uterine size

Hypermesis

Prominent theca lutein cysts

Q 14. A patient with a complete mole is found to have sizeable ovarian cysts that are presumed to be theca lutein cysts. All of the following are true about theca lutein cysts EXCEPT ?

Such cysts arise more frequently in patients with complete moles

Theca lutein cysts are more likely seen in patients with very high hCG levels

Cysts are filled with serious or serosanguinous fluid and are usually bilateral

Often require active management with surgical intervention

Q 15. With respect to gestational trophoblastic disease false statement include

chorioadenoma destruens is typically associated with theca-leutin ovarian cysts

HCG levels are invalidated by administration of the OCP

3% of women with complete molar pregnancy develop choriocarcinoma

choriocarcinoma responds to treatment with folic acid antagonists

Q 16. A case of gestational trophoblastic neoplasia belongs to high risk group if the disease develops after:

Hydatidiform mole

Full term pregnancy

Spontaneous abortion

Ectopic pregnancy

Q 17. Regarding Gestational Trophoblastic Disease true statement include

Complete mole paternal origin

Complete mole 46 XY Karyotype

Persistent GTN in Complete and partial mole 20%

Neoplasia occurs in 5%

Q 18. Regarding urinary bladder true statement include

Neck of external sphincter is formed by the smooth muscle of the bladder

External sphincter is usually under voluntary control

Trigone is a triangular area at the apex of the bladder

peritoneum entirely covers the bladder.

Q 19. Comparing complete hydatidiform moles gestations, complete hydatidiform mole gestations are more likely than partial moles to demonstrate all of these characteristics except?

more likely to require chemotherapy after evacuation for gestational trophablastic disease

more likely to present with a uterus large for dates

more likely to present with theca lutein cysts

more likely to ‘have focal rather than diffuse trophoblastic proliferation

Q 20. With regard to GTN USG characteristically shows

angular appearance

serrated appearance

criss cross pattern

snow storm appearance

Q 21. The most likely karyotype for patient with a partial mole would be ?

46, XX

46, XY

Diandric triploidy

Triploidy with two haploid sets of maternal origin

Q 22. Statements regarding lower urinary tract function in MS correct is

After 10 years of disease activity, >95% of MS patients will experience lower urinary tract symptoms.

The number of spinal cord lesions or extent of cord atrophy correlates well with specific urodynamic parameters.

Approximately 10% of patients with lower urinary tract symptoms and DSD demonstrate extensor plantar responses (Babinski’s sign) on clinical examination.

Detrusor sphincter dyssynergia is seen in >90% of patients with MS and lower urinary tract symptoms.

Q 23. A case of Gestational trophoblastic neoplasia is detected to have lung metastasis . She should be staged as

Stage I

Stage II

Stage III

Stage IV

Q 24. Which of the following statement about tumour markers is correct?

Carcino-embryonic antigen (CEA) is a tumour-specific marker in colorectal cancer

CEA is mainly used for determining prognosis and detecting relapse.

Human chorionic gonadotrophin (hCG) cannot be used to screen gestational trophoblastic disease in patients with molar pregnancy.

Raised hCG in peri-menopausal and post-menopausal women is always abnormal.

Q 25. The following are true of gestational trophoblastic disease

The incidence in the UK is about 1:50000 pregnancies

there is an increased incidence with increasing maternal age

the commonest genetic type is 46XY

bilateral theca lute in cysts are seen in over 90% of cases

Q 26. The most likely karyotype of patient with a complete mole would be ?

46, XX

46, XY

Diandric triploidy

Triploidy with two haploid sets of maternal origin

Q 27. A 29-year-old, gravida 2, para 0, at 19 weeks by last menstrual period, presents to the emergency department complaining of heavy vaginal bleeding. She is hemodynamically stable. Physical examination reveals a fundal height of 28 cm, and bright red blood in the vagina, with a closed cervix. Quantitative hCG is 190,000 mIU/mL. Ultrasound reveals absence of fetal tissue, diffuse, hydropic villi, and bilaterally enlarged ovaries with multiple, large, theca lutein cysts. What is the preferred management of this condition?

Bilateral ovarian cystectomies, with ovarian fi xation

Dilation and suction curettage, with concurrent bilateral ovarian cystectomies

Total abdominal hysterectomy and bilateral salpingo-oophorectomy

Dilation and suction curettage, under ultrasound guidance

Q 28. Regarding GTN true statement include

It is more common in UK caucasians than asians

Complete hydatiform mole is usually diploid with evidence of fetal tissue

Diagnosis of GTN can be made reliably at suction evacuation of the uterus

Persistent GTN may present with dyspnoea

Q 29. The highest incidence of Gestational Trophoblastic Disease is in:

Australia

Asia

North America

Westem Europe

Q 30. A patient with non-metastatic gestational trophoblastic disease can be treated with weekly intramuscular injections of which of the following agents ?

Cyclophosphamide

Carboplatinum

VP-16 (etoposide)

Methotrexate

Reproductive Biology / Medicine / Infertility MCQs – Exercise 21

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Reproductive Biology / Medicine / Infertility MCQs – Exercise 21

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